Familial hypercholesterolaemia

hypercholesterolemia /hy·per·cho·les·ter·ol·emia/ (-ko-les″ter-ol-e´me-ah) an excess of cholesterol in the blood.hypercholesterole´mic

familial hypercholesterolemia an inherited disorder of lipoprotein metabolism due to defects in the receptor for low-density lipoprotein (LDL), with xanthomas, corneal arcus, premature corneal atherosclerosis, and a type II-a hyperlipoproteinemia biochemical phenotype with elevated plasma LDL and cholesterol.

familial hypercholesterolemia

1. See type II familial hyperlipoproteinemia.

2. See hypercholesterolemia.

familial hypercholesterolemia.

See low-density lipoprotein receptor disorder.

hypercholesterolemia [hi″per-ko-les″ter-ol-e´me-ah]

excess of cholesterol in the blood.

familial hypercholesterolemia hyperlipoproteinemia (type II).

familial hypercholesterolemia

Metabolic disease A common–
1:500 congenital AD defect in the LDL receptor gene, resulting in dysfunctional or absent receptors Clinical Early CAD in ♂, first MI by age 40–♀ may be asymptomatic throughout life, tendinous xanthomas, corneal arcus, xanthelasma; homozygotes have LDL-C > 600 mg/dL, tuberous xanthomas and fatal CAD in adolescence Lab ↑ LDL-C–300-500 mg/dL-20% of
cholesterol in this range is due to FH Management Smoking cessation, diet, exercise, drugs–bile-acid binding resins–eg, cholestipol, cholestyramine, nicotinic acid, ↓ cholesterol and ↓ saturated fat diet, liver transplant may provide LDL receptors

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amlodipine besylate and atorvastatin calcium atorvastatin calcium Beta Propeller cholesterolemia Crestor diabetic xanthoma dominant ezetimibe ezetimibe/simvastatin familial hypercholesterolemia with hyperlipemia hemapheresis hypercholesteremia hypercholesterolemia hyperlipoproteinemia Lipitor lipoproteinemia lovastatin low-density lipoprotein receptor disorder Mevacor	It is estimated that up to 4,800 people may be unaware they have the potentially life-threatening familial hypercholesterolaemia (FH). Heart risk screening by Daily Post (Liverpool, England) The pioneering drop-in centre will provide advice and support to everyone who is concerned about cholesterol and inherited high cholesterol conditions such as familial hypercholesterolaemia. HEART UK comes to Sandwell by Birmingham Mail (England) Experts hope to identify up to 100,000 people with familial hypercholesterolaemia (FH), a genetic defect that causes high cholesterol. Doctors urged to screen families for heart defects by Coventry Evening Telegraph (England)	famciclovir famcyclovir familial familial adenomatous polyposis familial aggregation familial Alzheimer's disease familial amyloidosis familial autonomic dysfunction familial benign chronic pemphigus familial broad-beta hyperlipoproteinemia familial centrolobar sclerosis familial combined hyperlipidemia familial cretinism familial dysautonomia familial dysbetalipoproteinemia familial exudative vitreoretinopathy familial fat-induced hyperlipemia Familial Fatal Insomnia familial focal facial dermal dysplasia familial hemiplegic migraine familial Hibernian fever familial high-density lipoprotein deficiency familial histiocytic reticulosis familial hyperbetalipoproteinemia familial hyperbetalipoproteinemia and hyperprebetalipoproteinemia Familial hypercholesterolaemia familial hypercholesterolemia familial hypercholesterolemia with hyperlipemia familial hyperchylomicronemia familial hyperchylomicronemia with hyperprebetalipoproteinemia familial hyperglyceridemia familial hyperlipoproteinemia familial hyperprebetalipoproteinemia familial hypertriglyceridemia familial hypertrophic cardiomyopathy familial iminoglycinuria familial intestinal polyposis familial intraosseous fibrous swelling of the jaws familial juvenile nephronophthisis familial juvenile nephrophthisis familial lipoprotein lipase deficiency familial malignancy familial Mediterranean fever familial multiple endocrine familial nonhemolytic jaundice familial osteochondrodystrophy familial paroxysmal polyserositis familial periodic fever familial periodic paralysis familial polyendocrine adenomatosis familial polyposis	familial glomerulonephritis familial glomerulonephritis familial glomerulonephritis Familial Glucocorticoid Deficiency Familial HDL Deficiency familial hemiplegic migraine familial hemiplegic migraine Familial hemochromatosis Familial Hemophagocytic Lymphohistiocytosis Familial Hemophagocytic Lymphohistocytosis Familial Hibernian fever Familial High Density Lipoprotein Deficiency Disease familial high-density lipoprotein (HDL) deficiency familial high-density lipoprotein (HDL) deficiency familial high-density lipoprotein (HDL) deficiency familial high-density lipoprotein (HDL) deficiency familial high-density lipoprotein (HDL) deficiency familial high-density lipoprotein deficiency familial histiocytic reticulosis familial histiocytic reticulosis familial histiocytic reticulosis, histiocytic medullary reticulosis familial histiocytic reticulosis, histiocytic medullary reticulosis Familial histiocytosis with eosinophilia Familial History of Breast Carcinoma Familial Horizontal Gaze Palsy with Progressive Scoliosis Familial Hyperaldosteronism Type I familial hyperbetalipoproteinemia familial hyperbetalipoproteinemia and hyperprebetalipoproteinemia Familial hypercalcemia with nephrocalcinosis and indicanuria Familial Hypercholanemia Familial hypercholesterolaemia familial hypercholesterolemia familial hypercholesterolemia familial hypercholesterolemia with hyperlipemia familial hyperchylomicronemia familial hyperchylomicronemia with hyperprebetalipoproteinemia familial hyperglyceridemia Familial Hyperkalemic Periodic Paralysis familial hyperlipoproteinemia familial hyperprebetalipoproteinemia Familial Hyperreninemic Hypoaldosteronism familial hypertriglyceridemia familial hypertriglyceridemia familial hypertrophic cardiomyopathy familial hypertrophic cardiomyopathy Familial Hypoalphalipoproteinemia Familial hypobetalipoproteinemia Familial hypobetalipoproteinemia Familial hypobetalipoproteinemia Familial Hypocalciuric Hypercalcemia Familial Hypokalemic Periodic Paralysis Familial Hypokalemic Periodic Paralysis familial hypophosphatemia familial hypophosphatemia familial hypophosphatemic rickets familial hypophosphatemic rickets familial hypophosphatemic rickets Familial Idiopathic Basal Ganglia Calcification Familial Idiopathic Gonadotropin Deficiency Familial Idiopathic Low-Molecular-Weight Proteinuria Familial Idiopathic Nonarteriosclerotic Cerebral Calcification

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amlodipine besylate and atorvastatin calcium
atorvastatin calcium
Beta Propeller
cholesterolemia
Crestor
diabetic xanthoma
dominant
ezetimibe
ezetimibe/simvastatin
familial hypercholesterolemia with hyperlipemia
hemapheresis
hypercholesteremia
hypercholesterolemia
hyperlipoproteinemia
Lipitor
lipoproteinemia
lovastatin
low-density lipoprotein receptor disorder
Mevacor

It is estimated that up to 4,800 people may be unaware they have the potentially life-threatening familial hypercholesterolaemia (FH).

Heart risk screening by Daily Post (Liverpool, England)

The pioneering drop-in centre will provide advice and support to everyone who is concerned about cholesterol and inherited high cholesterol conditions such as familial hypercholesterolaemia.

HEART UK comes to Sandwell by Birmingham Mail (England)

Experts hope to identify up to 100,000 people with familial hypercholesterolaemia (FH), a genetic defect that causes high cholesterol.

Doctors urged to screen families for heart defects by Coventry Evening Telegraph (England)

famciclovir

famcyclovir

familial

familial adenomatous polyposis

familial aggregation

familial Alzheimer's disease

familial amyloidosis

familial autonomic dysfunction

familial benign chronic pemphigus