familial centrolobar sclerosis

sclerosis /scle·ro·sis/ (-ro´sis) an induration or hardening, especially from inflammation and in diseases of the interstitial substance; applied chiefly to such hardening of the nervous system or to hardening of the blood vessels.

amyotrophic lateral sclerosis Lou Gehrig disease: progressive degeneration of the neurons that give rise to the corticospinal tract and of the motor cells of the brain stem and spinal cord, resulting in a deficit of upper and lower motor neurons; it usually has a fatal outcome within 2 to 3 years.

arterial sclerosis arteriosclerosis.

arteriolar sclerosis arteriolosclerosis.

diffuse cerebral sclerosis the infantile form of metachromatic leukodystrophy.

disseminated sclerosis multiple s.

familial centrolobar sclerosis Pelizaeus-Merzbacher disease.

glomerular sclerosis glomerulosclerosis.

hippocampal sclerosis loss of neurons in the region of the hippocampus, with gliosis; sometimes seen in epilepsy.

lateral sclerosis degeneration of the lateral columns of the spinal cord, leading to spastic paraplegia. See amyotrophic lateral sclerosis and primary lateral sclerosis

Mönckeberg's sclerosis see under arteriosclerosis.

multiple sclerosis (MS) demyelination occurring in patches throughout the white matter of the central nervous system, sometimes extending into the gray matter; symptoms of lesions of the white matter are weakness, incoordination, paresthesias, speech disturbances, and visual complaints.

primary lateral sclerosis a form of motor neuron disease in which the degenerative process is limited to the corticospinal pathways.

progressive systemic sclerosis systemic scleroderma.

tuberous sclerosis an autosomal dominant disease characterized by hamartomas of the brain (tubers), retina, and viscera; mental retardation; seizures; and adenoma sebaceum.

familial centrolobar sclerosis.

See Pelizaeus-Merzbacher disease.

sclerosis [sklĕ-ro´sis]

an induration or hardening, especially of a part from inflammation, or in disease of the interstitial substance. The term is used chiefly for such a hardening of the nervous system due to hyperplasia of the connective tissue or for hardening of the blood vessels. Called also induration. adj., adj sclerot´ic.

amyotrophic lateral sclerosis see amyotrophic lateral sclerosis.

arteriolar sclerosis arteriolosclerosis.

disseminated sclerosis multiple sclerosis.

familial centrolobar sclerosis a progressive familial form of leukoencephalopathy marked by nystagmus, ataxia, tremor, parkinsonian facies, dysarthria, and mental deterioration.

focal glomerular sclerosis focal segmental glomerulosclerosis.

glomerular sclerosis glomerulosclerosis.

hippocampal sclerosis loss of neurons in the region of the hippocampus, with gliosis; sometimes seen in epilepsy.

lateral sclerosis a form seated in the lateral columns of the spinal cord. It may be primary, with spastic paraplegia, rigidity of the limbs, and increase of the tendon reflexes but no sensory disturbances, or secondary to myelitis, with paraplegia and sensory disturbance.

medial calcific sclerosis (Mönckeberg's sclerosis) Mönckeberg's arteriosclerosis.

multiple sclerosis see multiple sclerosis.

systemic sclerosis systemic scleroderma.

tuberous sclerosis a congenital heredofamilial disease, transmitted as an autosomal dominant trait, characterized principally by the presence of hamartomas of the brain (tubers), retina (phakomas), and viscera, mental retardation, seizures, and adenoma sebaceum, and often associated with other skin lesions.

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amyotrophic lateral sclerosis aplasia aplasia cutis congenita arterial sclerosis Bourneville's disease focal glomerular sclerosis medial calcific sclerosis multiple sclerosis Pelizaeus-Merzbacher disease primary lateral sclerosis progressive systemic sclerosis sclerosis systemic sclerosis tuberous sclerosis	false-negative rate false-negative reaction false-positive false-positive rate false-positive reaction falsification falsification of clinical credentials falsify Falstaff Snore falx falx cerebelli falx cerebri falx inguinalis falx ligamentosa FAM famciclovir famcyclovir familial familial adenomatous polyposis familial aggregation familial Alzheimer's disease familial amyloidosis familial autonomic dysfunction familial benign chronic pemphigus familial broad-beta hyperlipoproteinemia familial centrolobar sclerosis familial combined hyperlipidemia familial cretinism familial dysautonomia familial dysbetalipoproteinemia familial exudative vitreoretinopathy familial fat-induced hyperlipemia Familial Fatal Insomnia familial focal facial dermal dysplasia familial hemiplegic migraine familial Hibernian fever familial high-density lipoprotein deficiency familial histiocytic reticulosis familial hyperbetalipoproteinemia familial hyperbetalipoproteinemia and hyperprebetalipoproteinemia familial hypercholesterolemia familial hypercholesterolemia with hyperlipemia familial hyperchylomicronemia familial hyperchylomicronemia with hyperprebetalipoproteinemia familial hyperglyceridemia familial hyperlipoproteinemia familial hyperprebetalipoproteinemia familial hypertriglyceridemia familial hypertrophic cardiomyopathy familial iminoglycinuria familial intestinal polyposis	Familial amyotrophic lateral sclerosis Familial amyotrophic lateral sclerosis Familial and Hereditary Inclusion Body Myopathy familial apolipoprotein C-II (apo C-II) deficiency familial apolipoprotein C-II (apo C-II) deficiency familial apolipoprotein C-II (apo C-II) deficiency familial apolipoprotein C-II (apo C-II) deficiency familial apolipoprotein C-II (apo C-II) deficiency Familial atrial fibrillation Familial atrial fibrillation Familial Atypical Cold Urticaria Familial Atypical Mole and Melanoma Familial Atypical Multiple Mole Melanoma familial atypical multiple mole melanoma-pancreatic cancer syndrome Familial Autoimmune Myasthenia Gravis familial autonomic dysfunction Familial Benign familial benign chronic pemphigus familial benign chronic pemphigus Familial benign giant-cell tumor of the jaw familial benign hypercalcemia Familial British Dementia familial broad-beta hyperlipoproteinemia Familial Bullous Lichen Planus Familial cancer Familial cancer Familial cancer Familial Cancer Database Familial Carpal Tunnel Syndrome Familial Cavernous Hemangioma familial centrolobar sclerosis familial chloride diarrhea familial chloride diarrhea familial chloride diarrhea familial cluster familial cluster familial cluster Familial Cold Autoinflammatory Syndrome Familial Cold Urticaria familial combined hyperlipidemia familial combined hyperlipidemia familial combined hyperlipidemia Familial Continual Skin Peeling Familial Continuous Skin Peeling familial convulsions and ataxia of cattle familial convulsions and ataxia of cattle familial convulsions and ataxia of cattle familial cretinism Familial Creutzfeldt-Jakob Disease Familial Danish Dementia Familial Digital Arthropathy-Brachydactyly Familial Disautonomia Familial Disautonomia familial disease familial disease familial disease familial disease Familial Distal Renal Tubular Acidosis familial dysautonomia familial dysautonomia familial dysautonomia

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