familial cancer


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fa·mil·i·al can·cer

cancer aggregating among blood relatives; rarely the mode of inheritance is clearly mendelian, either dominant, as in retinoblastoma, basal cell nevus syndrome, neurofibromatosis, and intestinal polyposis, or recessive, as in xeroderma pigmentosum.
See also: cancer family.
References in periodicals archive ?
Lancaster said he feels strongly that they should be followed by a gynecologic oncologist or a physician with expertise in dealing with familial cancer syndromes.
Although a family history of testicular cancer probably accounts for less than five percent of all testicular cancers, the careful study of rare familial cancer clusters has often led to important new understanding of the non-familial versions of the same cancer.
Since the discovery of the BRCA1 and BRCA2 genes, genetic counselors have been integral to the application of this technology in patient care," explained Cecelia Bellcross, co-chair of the Familial Cancer Genetic Counseling Special Interest Group of NSGC.
Additional research is underway to find out how environmental factors may influence familial cancer development.
This includes patients with familial cancer syndromes and relatives of those who have tested positive for a mutation in one of the two breast and ovarian cancer genes.
If the brief history suggests a potential pattern of familial cancer, the physician may recommend the patient complete a more comprehensive evaluation, called GenRISK(TM).
This year's Mott award winners discovered Li-Fraumeni syndrome, a familial cancer syndrome which can now be detected through a genetic testing program pioneered by this pair of researchers.
Familial cancers, cluster cancers and multiple cancers in the same individual have become frequent in Iraq," states Dr.
TP53 mutations can lead to multiple familial cancers with characteristic genetic patterns.

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