Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.
fa·mil·i·al am·y·loid neu·rop·a·thy[MIM*105120, various kinds]
a disorder in which various peripheral nerves are infiltrated with amyloid and their functions disturbed; an abnormal prealbumin is also formed and is present in the blood; characteristically, it begins during midlife and is found largely in patients of Portuguese descent; autosomal dominant inheritance. Other rare clinical types occur.
The only inherited form of amyloidosis. In this variant of the disease, transthyretin is manufactured by the liver and deposits in a wide variety of tissues, causing them to malfunction.
See also: amyloidosis