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familial aggregation |
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aggregation /ag·gre·ga·tion/ (ag″rĕ-ga´shun) 1. massing or clumping of materials or people together. 2. a clumped mass of material. familial aggregation the occurrence of more cases of a given disorder in close relatives of a person with the disorder than in control families. platelet aggregation a clumping together of platelets induced by various agents (e.g., thrombin) as part of the mechanism leading to thrombus formation.
aggregation 1. massing or clumping of materials together. 2. a clumped mass of material. familial aggregation the occurrence of more cases of a given disorder in close relatives of an animal with the disorder than in control families. platelet aggregation platelet agglutination. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Both genetic inheritance and sharing of common environment in the same family explain the increased risk of PD of relatives of PD cases compared with relatives of controls in familial aggregation studies. 3) However, after including familial aggregation (representing effects of shared genetic and family influences) in the model, the variance explained by lean body mass dropped to 8%. Familial Aggregation of Parkinson's Disease in Iceland Sveinbjornsdottir S, Hicks AA, Jonsson T, et al (National University Hospital and deCODE genetics, Reykjavik, Iceland; Department of Human Genetics, University of Chicago, Chicago, Ill), N Engl J Med. |
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