familial Alzheimer's disease


Also found in: Acronyms.

familial Alzheimer's disease

n.
An inherited form of Alzheimer's disease caused by a defect on a particular chromosome.
References in periodicals archive ?
Though early-onset, familial Alzheimer's disease (fAD) accounts for a small number of AD cases, the study of fAD patients, or samples in this case, can reveal important aspects of the cell and molecular mechanisms underlying all types of AD.
Especially DIAN is performed with mutation carriers before the onset of familial Alzheimer's disease, thus outcome is expected.
Candidate gene for the chromosome 1 familial Alzheimer's disease locus," Science, vol.
Neuropsychological profile of a large kindred with familial Alzheimer's disease caused by the E280A single presenilin-1 mutation.
The findings "are consistent with observations in late-onset Alzheimer's disease and support behavioral changes in familial Alzheimer's disease being a state associated with incipient Alzheimer's pathology rather than a life-long disposition," Dr.
Cloning of a gene bearing missense mutation in early-onset familial Alzheimer's disease.
A study of persons destined to develop familial Alzheimer's disease (FAD) can help us differentiate between such symptoms as a 'trait' associated with a predisposition to AD or a 'state' related to the incipient development of AD pathology," he said.
A study of persons destined to develop familial Alzheimer's disease (FAD) "can help us differentiate between such symptoms as a "trait' associated with a predisposition to AD or a 'state" related to the incipient development of AD pathology," he said.
In familial Alzheimer's disease, mutations in a gene associated with the production of amyloid beta protein give rise to abnormal accumulations in the brain of amyloid plaques.
Elevation of [beta]-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.
Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14.

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