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extrinsic pathway

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Extrinsic pathway
One of three pathways in the coagulation cascade.

extrinsic
of external origin.

extrinsic allergic alveolitis
see hypersensitivity pneumonitis.
extrinsic factor
see extrinsic factor.
extrinsic incubation period
the period between infection of the arthropod insect vector and the vector's ability to infect the next vertebrate host.
extrinsic pathway
see coagulation pathways.
extrinsic protein
see membrane proteins.

extrinsic pathway
Hematology The arm of coagulation activation which, like the intrinsic pathway, converges on the common pathway, ie factor X activation; the EP is activated by exposure of blood to tissue factor, circulating factor VII, Ca2+ and phospholipid. Cf Common pathway, Intrinsic pathway.


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DIAGNOSIS Bleeding diathesis with hemophilic arthropathy DISCUSSION There are 2 major types of hemophilia: hemophilia A (classic hemophilia), which is a functional deficiency of Factor VIII of the intrinsic pathway of coagulation; and hemophilia B (Christmas disease), which is a functional deficiency of Factor IX of the extrinsic pathway of coagulation.
There are two ways to do this: a so-called intrinsic pathway and a so-called extrinsic pathway.
 
 
 
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