2) At radical prostatectomy (RP) ductal cancer is associated with a higher incidence of positive surgical margins, extraprostatic
extension, vascular invasion, seminal vesicle invasion, and metastases.
These are men who have specific risk factors for cancer recurrence, including positive surgical margins, pathological stage T3 disease (seminal vesicle invasion, extraprostatic
extension, bladder neck invasion) or rising PSA after initial PSA nadir.
For example, oral administration of modified citrus pectin inhibited the spontaneous extraprostatic
colonization of injected cells from a prostate cancer cell line and in a dose-dependent fashion.
For pT3 control cases, we used all continuous, GS-matched pT3 prostatectomies without matching to either extraprostatic
extension (pT3a) or seminal vesicle invasion (pT3b).
The tumor type, Gleason score, tertiary pattern, perineural invasion, extraprostatic
extension, seminal vesicle invasion, surgical margin, lymph nodes, pathological stage, vascular invasion, tumor location, non-neoplastic prostate tissue, high-grade PIN and tumor volume were investigated and reported.
Association of cigarette smoking with extraprostatic
prostate cancer in young men.
We defined advanced cases by a diagnosis of extraprostatic
or metastatic cancer involving lymph nodes or other organs ar hrst diagnosis of prostate cancer.
In the late seventies and early eighties, a high proportion of patients with prostate cancer detected by digital rectal examination alone had a high probability of node-positive disease in addition to having a greater chance of extraprostatic
However, the association between antibody presence and aggressive prostate cancer was significant: extraprostatic
prostate cancer (OR = 2.
In prostate cancer staging, it is important to differentiate between stage T2 (disease confined to the prostate) and T3 extraprostatic
population-based studies of men who underwent radical prostatectomies for localized prostate cancer showed that 35%-47% needed further anticancer therapy within 5 years and 47% had extraprostatic
disease on pathology after the prostatectomy.
To this end, measurements of free and total PSA performed up to 10 years before diagnosis of PCa with extraprostatic
extension, lymph node or bone metastases have been compared to a group of men who had PCa with a more favorable pathology.