extracellular space


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extracellular space

extracellular space

Abbreviation: EC space
The space between cells. It contains tissue fluid, the water derived from plasma in the adjacent capillaries. The water flows among capillaries, tissue spaces, and cells.
See: extracellular fluid
See also: space

extracellular

situated or occurring outside a cell or cells.

extracellular constituents
all of the constituents of the body outside the cells; include water, electrolytes, protein, glucose, enzymes, hormones.
extracellular fluid
all of the body fluid lying outside the cells. Includes intravascular fluid or plasma and the interstitial fluid. That part of the extracellular fluid that is in special cavities which have special characteristics, e.g. synovial fluid, urine, aqueous humor of eye, are called transcellular fluids.
extracellular matrix
the network of proteins and carbohydrates that surround a cell or fill the intercellular spaces.
extracellular space
References in periodicals archive ?
Our findings indicate that both 6-HITC and SFN activate Nrf2, resulting in up-regulation of GCL and the GSTs and MRPs responsible for conjugation of MeHg with GSH and excretion of the MeHg-GSH adduct into the extracellular space.
A reduction of steady-state levels of MeHg in cells is associated with diminished chemical modification of cellular proteins, confirming the importance of formation of the MeHg-GSH adduct, and its excretion into the extracellular space, in the detoxification of MeHg.
The virus particles seen in the extracellular space were apparently released prior to heat treatment of the tumors (Fig.
In these studies, phase angle indicates cell membrane potential and water distribution between the intra- and extracellular spaces and is used widely in human medicine as a means to measure nutritional status, but it has never been applied to fish or lower vertebrates.
Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces.
People with cystic fibrosis have a defective or missing version of a protein responsible for, among other things, releasing glutathione into the extracellular spaces.
A key difference between direct injection and PMED delivery is the efficiency with which this is done: Direct injection delivers the DNA to extracellular spaces and relies on an inefficient, non-specific uptake of the DNA by neighboring cells or transport along lymphatic vessels to draining lymph nodes.
While engineering megakaryocytes and platelets for infusion into their mouse models of Hurler, the scientists report they were able to release IDUA directly into amply sized extracellular spaces or inside micro-particles as the cells matured or activated.
She had suffered cerebral oedema, a condition characterised by excess accumulation of water in the intracellular or extracellular spaces of the brain.
Sphingolipids are found in the extracellular spaces of the stratum corneum, where they play a critical role in strengthening the barrier function of the skin, promoting moisture retention and increasing elasticity of the skin, according to the company.
The major pathological mechanism underlying ischemic/ reperfusion injury to brain tissue is a phenomenon known as 'excitotoxicity' in which excessive release of glutamate (which builds up in the extracellular spaces after stroke onset) causes an inappropriate activation of ionotropic N-methyl-d-aspartate (NMDA) receptors in the brain.

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