extracellular matrix


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extracellular matrix

the aggregate of proteins secreted by cells.

extracellular matrix

a substance containing collagen, elastin, proteoglycans, glycosaminoglycans, and fluid, produced by cells and in which the cells are embedded. The matrix secreted by chondroblasts, for example, is responsible for the properties of cartilage.

extracellular matrix

Non-living material secreted by cells that fills spaces between the cells in a tissue, protecting them and helping to hold them together. The extracellular matrix may be semifluid or rigidly solid and hard as in bone. It is composed mainly of protein and includes collagens, elastin, reticulin, glycoproteins, proteoglycans, fibronectin, laminins and osteopontin.

extracellular matrix (ECM)

see MATRIX.

extracellular matrix (eksˈ·tr·selˑ·y·ler māˑ·triks),

n substance produced by cells and secreted into the environment in which the cells are embedded; contains collagen, proteoglycans, glycosaminoglycans, and fluid; can influence the behavior of the cells. Also called
ECM. See also connective tissue.

extracellular

situated or occurring outside a cell or cells.

extracellular constituents
all of the constituents of the body outside the cells; include water, electrolytes, protein, glucose, enzymes, hormones.
extracellular fluid
all of the body fluid lying outside the cells. Includes intravascular fluid or plasma and the interstitial fluid. That part of the extracellular fluid that is in special cavities which have special characteristics, e.g. synovial fluid, urine, aqueous humor of eye, are called transcellular fluids.
extracellular matrix
the network of proteins and carbohydrates that surround a cell or fill the intercellular spaces.
extracellular space
References in periodicals archive ?
The collagen family: structure, assembly, and organization in the extracellular matrix.
offers the next generation of regenerative medicine through the development and commercialization of unique extracellular matrix products to repair and remodel damaged tissues in a broad range of applications.
Under normal circumstances, fat cells continue to grow until they reach a point where the extracellular matrix they've built around themselves is so strong that it's no longer flexible.
Indeed, investigators have found that cells from very different organs and tissues become almost indistinguishable when removed from their normal extracellular matrix and placed on glass or plastic surfaces.
Our data provide the first evidence that a selected population of marrow cells can connect the epidermis and dermis in a mouse model of the disease and offer a potentially valuable approach for treatment of human RDEB and other extracellular matrix disorders.
Mesynthes's Endoform[TM] technology utilizes a proprietary extracellular matrix biomaterial containing a complex mixture of important biological molecules, including structural and adhesive proteins, such as collagens, elastin, fibronectin and laminin, and glycosaminoglycans.
Osteocalcin is the most abundant of several noncollagen proteins in the extracellular matrix of bone.
Nasdaq:HALO), a biopharmaceutical company developing and commercializing products targeting the extracellular matrix, today announced its participation in the 28th Annual J.
Halozyme Therapeutics is a biopharmaceutical company developing and commercializing products targeting the extracellular matrix for the diabetes, cancer, dermatology and drug delivery markets.
To examine just how this extracellular matrix affects the cells attached to it, biologists are growing cells on laboratory plates, where the cell's semisolid support and surrounding solution can be manipulated directly.
Nasdaq:HALO), a biopharmaceutical company developing and commercializing products targeting the extracellular matrix, today announced that it will host a meeting for analysts and investors on October 15 in New York.
Nasdaq: HALO), a biopharmaceutical company developing and commercializing products targeting the extracellular matrix, today announced it plans to report third quarter 2011 financial results on Monday, November 7, 2011 after the close of the financial markets.

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