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external ophthalmoplegia

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ophthalmoplegia /oph·thal·mo·ple·gia/ (of-thal″mo-ple´jah) paralysis of the eye muscles.ophthalmople´gic
external ophthalmoplegia  paralysis of the external ocular muscles.
internal ophthalmoplegia  paralysis of the iris and ciliary apparatus.
nuclear ophthalmoplegia  that due to a lesion of nuclei of motor nerves of the eye.
Parinaud's ophthalmoplegia  paralysis of conjugate upward movement of the eyes without paralysis of convergence, associated with midbrain lesions.
partial ophthalmoplegia  that affecting some of the eye muscles.
progressive external ophthalmoplegia  gradual paralysis affecting the extraocular muscles, and sometimes also the orbicularis oculi, leading to ptosis and progressive total ocular paresis.
total ophthalmoplegia  paralysis of all the eye muscles, both intraocular and extraocular.

external ophthalmoplegia
n.
Paralysis affecting one or more of the extrinsic eye muscles.


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The defects decrease energy production and lead to exercise intolerance, cramps, myoglobinuria, weakness in the muscles around the eye leading to droopy eyelids (ptosis), and external ophthalmoplegia (weakness of the eye muscles) (25).
This particular patient had a long medical history in which signs of mitochondrial dysfunction had been evident for a number of years (the patient's comorbidities of diabetes, heart failure and visual symptoms are also highly suggestive of chronic progressive external ophthalmoplegia, a potential clinical presentation of a mitochondrial disorder).
 
 
 
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