We observed these enhanced responses in MCF-7 cells only when cells were cotransfected with ER expression vectors
, indicating that the presence of the ER expression vector
is necessary for this effect.
Tsujimoto (University of Osaka, Japan) for providing a bcl-2 expression vector
Electroporation significantly enhances cellular uptake of pharmacologically useful compounds and expression vectors
such as DNA plasmids.
Novartis AG (Basel, Switzerland) has patented BIV constructs encompassing BIV combination vectors, BIV vectors and BIV packaging vectors and particularly the invention pertains to a three vector system comprising: a) a BIV vector construct including a DNA segment from a BIV genome, a packaging sequence to package RNA into virions; a promoter operably linked to the DNA segment; and a transgene operably linked to a second promoter; b) a BIV packaging vector construct comprising a BIV DNA sequence fragment comprising at least a gag gene or pol gene of BIV; a promoter operably linked to the BIV DNA fragment; and a polyadenylation sequence located downstream of the BIV DNA fragment; and c) an expression vector
construct comprising a gene encoding a viral surface protein.
It is a pleasure to be applying our Baculovirus Expression Vector
System (BEVS) technology for the development of a new and novel vaccine for the treatment of hepatitis B," said Manon Cox, Chief Operating Officer of Protein Sciences Corporation.
Also, the invention relates to expression vector
into which the human cyclin I gene is incorporated as well as to a transformant into which the vector is introduced.
OTCBB:CYGX) has entered into an agreement with scientists at Louisiana State University Health Sciences Center, Shreveport for preclinical experiments using the company's ssDNA expression vector
technology to silence a gene that has been shown to cause malignant transformation of tumor cells.
OTCBB:CYGX) has entered into an agreement with scientists at Baylor College of Medicine for experiments using a combination of the company's ssDNA expression vector
technology and Baylor's proprietary aerosol gene delivery technology against a gene that, when silenced, inhibits tumor metastasis.
Also disclosed is a novel DNA expression vector
useful for making cells as described above.
Tan's paper is titled "DNA Enzyme Generated by a Novel Single-Stranded DNA Expression Vector
Inhibits Expression of the Essential Bacterial Cell Division Gene ftsZ," and it will be published in the next few weeks.
The gene can be introduced into a mammalian host by way of an expression vector
either as naked DNA or complexed to lipid carriers, particularly cationic lipid carriers.
The siRNA expression vector
technology is an important addition to this product line.