expanded disability status scale


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expanded disability status scale (EDSS),

a commonly used rating system for evaluating the degree of neurologic impairment in multiple sclerosis, based on neurologic findings, and not symptoms; there are 10 grades in all, in steps and half-steps (for example, 4, 4.5, 5), with "1" being neurologically normal and "10" being death.

ex·pand·ed dis·a·bil·i·ty sta·tus scale

(EDSS) (eks-pand'ĕd dis'ă-bil'i-tē stat'us skāl)
A commonly used rating system for evaluating the degree of neurologic impairment in multiple sclerosis, based on neurologic findings, and not symptoms; there are 10 grades in all, in steps and half-steps (e.g., 4, 4.5, 5), with "1" neurologically normal and "10" dead.
Synonym(s): Kurtzke multiple sclerosis disability scale.
References in periodicals archive ?
Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS).
2 (*) EDSS = expanded disability status scale (**) Multiple answers per patient possible
Abbreviations: ABC = Activities-specific Balance Confidence, EDSS = Expanded Disability Status Scale, FES-I = Falls Efficacy Scale-International, MRI = magnetic resonance imaging, MS = multiple sclerosis, MSWS-12 = MS Walking Scale-12, PwMS = people with MS, RMS = root mean square, SOT = Sensory Organization Test.
These results suggest that higher doses and frequencies of interferon beta may not necessarily be better when you take into account the comparable disease progression as assessed by the Expanded Disability Status Scale (EDSS1) and the fact that patients treated with AVONEX (r) could have significant advantages in the long term due to this treatment's low incidence of neutralizing antibodies (NAbs) and its once-weekly dosing, which encourages better long term adherence to therapy".
His name, if not his work, is familiar to many people with MS today through their experience with the Expanded Disability Status Scale -- he EDSS or commonly, the Kurtzke scale.
Kurtzke JF: Rating neurologic impairment in multiple sclerosis: An Expanded Disability Status Scale.
5 percent reduction in the risk of 12-week sustained accumulation of disability, the main secondary endpoint, as measured by the Expanded Disability Status Scale (EDSS), compared to placebo (p=0.
The sample had a range of Expanded Disability Status Scale (EDSS) scores between 0 and 6.
After the third year of the study, the researchers found that those who had been receiving the drug three times a week or once a week for the duration of the trial were less likely to be diagnosed with clinically definite MS (defined as having a second clinical attack or a sustained increase in the Expanded Disability Status Scale disability score of greater than 1.
They had a mean age of 38 years, a mean disease duration of 8 years, and a mean Expanded Disability Status Scale score of 3.
The researchers used a measuring technique called the Kurtzke Expanded Disability Status Scale (EDSS) to assess the progression of the disease.
A report on MS in children noted that a high proportion had cognitive impairment, which was not closely linked to disability as measured by the Expanded Disability Status Scale (EDSS).

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