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exotoxin |
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exotoxin /exo·tox·in/ (ek´so-tok″sin) a potent toxin formed and excreted by the bacterial cell, and free in the surrounding medium.ex´otoxic streptococcal pyrogenic exotoxin one produced by Streptococcus pyogenes, existing in several antigenic types and causing fever, the rash of scarlet fever, organ damage, increased blood-brain barrier permeability, and alterations in immune response.
Exotoxin A poisonous secretion produced by bacilli which is carried in the bloodstream to other parts of the body. Mentioned in: Diphtheria exotoxin [ek′sətok′sin] Etymology: Gk, exo + toxikon, poison a toxin that is secreted or excreted by a living microorganism. Compare endotoxin. exotoxin (ek´sōtoksin), n the toxic material formed by microorganisms and subsequently released into their surrounding environments. exotoxin a potent toxin formed and secreted by the bacterial cell, and found free in the surrounding medium. Exotoxins are generally heat labile, and are protein in nature. Many can be detoxified with retention of antigenicity by treatment with formaldehyde (toxoid). Many are important virulence factors in pathogenic bacteria. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Using antimicrobial drug susceptibility testing, staphylococcal cassette chromosome mec typing, exotoxin profiling, and pulsed-field gel electrophoresis typing, we provide evidence that supports the relationship between nasal strains of PVL-positive MRSA and community-acquired disease. Look, for example, at the presence of Pseudomonas exotoxin A in the inner ear, which has been shown to have lasting deleterious effects on the inner ear. Penicillin and clindamycin differentially inhibit the production of pyrogenic exotoxins A and B by group A streptococci. |
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