16) BCM-7 can also be hydrolyzed further to produce the shorter exorphin
with greater opioid receptor binding affinity, beta-casomorphin-5 (BCM-5).
Opioid peptides derived from food proteins: The exorphins.
Exorphins are morphinelike molecules derived from incomplete digestive breakdown of the common food allergens dairy and grain.
For example, wheat and dairy products contain exorphins
(they're like endorphins but not made in the body), which bind to opiate receptors in the brain and produce a euphoric, even drug-like haze.
In addition, casein, a milk protein concentrated in cheese, also contains a source of opiate-like compounds called exorphins
are other food chemicals cited by advocates of the stone-age diet.
These potent endorphins and exorphins
give us pleasurable, comforting sensations we can get hooked on.
Table 5: Increased Intestinal Permeability Conditions Associated Antigens/Agents Associated Coeliac Enteropathy Gluten Crohn's Disease Other IBD Casein & dairy exorphins
Alcohol consumption Varies with individual Drug Effects Alcohol Autoimmune Syndromes (?
Many investigators have reported behavioral improvements with avoidance of dietary gluten and casein, presumably by lowering exposure to exorphins
He noted that alterations of gut barrier function are common and well-documented in these children and that the absorption of exorphins
from incompletely digested casein and gluten may significantly contribute to the neurological manifestations of autism.