Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
3,911,911,038 visitors served.
forum Join the Word of the Day Mailing List For webmasters
?
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

exonuclease
(redirected from Exonucleases)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.03 sec.
exonuclease /exo·nu·cle·ase/ (ek″so-noo´kle-ās) any nuclease specifically catalyzing the hydrolysis of terminal bonds of deoxyribonucleotide or ribonucleotide chains, releasing mononucleotides.
ex·o·nu·cle·ase (ks-nkl-s, -z)
n.
Any of a group of enzymes that catalyze the hydrolysis of single nucleotides from the end of a DNA or RNA chain.

exonuclease
[ek′sōno̅o̅′klē·ās]
Etymology: Gk, exo + L, nucleus, nut; ase, enzyme
an enzyme that digests DNA or RNA from the ends of the strands. Compare endonuclease.

exonuclease [ek″so-noo´kle-ās]
an enzyme that cleaves single mononucleotides from the end of a polynucleotide chain.

exonuclease
a nuclease that cleaves single mononucleotides from the end of a polynucleotide chain.

exonuclease III
one from E. coli that removes nucleotides from the 3′ ends of double-stranded DNA.


Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Feedback
Add definition
Mentioned in?  References in periodicals archive?   Medical browser?   Full browser?
 
5 and 5 Gy irradiation was almost identical in the wild-type (WT) A549 and Cter3 cells, implying that hPNK is not required for homologous recombination and that the processing of strand-break termini in this repair pathway is handled by a different set of enzymes including exonucleases and endonucleases, such as the WRN helicase/nuclease and Mre11 exonuclease (36, 37).
There are two types of DNases: exonucleases act on the end of a DNA chain, while endonucleases attack interior linkages.
Accordingly, enzymes called exonucleases pick up where UDGases and other base cutters leave off, excising damaged nucleotides.
 
 
 
Medical Dictionary
?

Terms of Use | Privacy policy | Feedback | Advertise with Us | Copyright © 2012 Farlex, Inc.
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.