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exonuclease

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
exonuclease /exo·nu·cle·ase/ (ek″so-noo´kle-ās) any nuclease specifically catalyzing the hydrolysis of terminal bonds of deoxyribonucleotide or ribonucleotide chains, releasing mononucleotides.
ex·o·nu·cle·ase (ks-nkl-s, -z)
n.
Any of a group of enzymes that catalyze the hydrolysis of single nucleotides from the end of a DNA or RNA chain.

exonuclease
[ek′sōno̅o̅′klē·ās]
Etymology: Gk, exo + L, nucleus, nut; ase, enzyme
an enzyme that digests DNA or RNA from the ends of the strands. Compare endonuclease.

exonuclease [ek″so-noo´kle-ās]
an enzyme that cleaves single mononucleotides from the end of a polynucleotide chain.

exonuclease
a nuclease that cleaves single mononucleotides from the end of a polynucleotide chain.

exonuclease III
one from E. coli that removes nucleotides from the 3′ ends of double-stranded DNA.


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3) showed that hPNK expression could partially rescue the sensitivity to oxidative damaging agents of the Escherichia coli DNA repair-deficient exonuclease IIIendonuclease IV double mutant.
Primers and unincorporated deoxynucleotide triphosphates were removed by using Microcon YM (Millipore, Billerica, MA, USA) technology or exonuclease I and shrimp alkaline phosphatase (Amersham, Piscataway, NJ, USA) (Figure 2).
There are two types of DNases: exonucleases act on the end of a DNA chain, while endonucleases attack interior linkages.
 
 
 
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