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pyrogen
(redirected from exogenous pyrogen)

    Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.03 sec.
pyrogen /py·ro·gen/ (pi´ro-jen) a fever-producing substance.
py·ro·gen (pr-jn)
n.
A substance that produces a fever.
Pyrogen
A chemical circulating in the blood that causes a rise in body temperature.
Mentioned in: Fever
pyrogen
[pī′rəjən]
Etymology: Gk, pyr, fire, genein, to produce
any substance or agent that tends to cause a rise in body temperature, such as some bacterial toxins. See also fever. pyrogenic, adj.
pyrogen
an agent that causes fever.
endogenous pyrogen (EP)
the mediator of fever, produced by polymorphonuclear leukocytes, monocytes and macrophages.
exogenous pyrogen
lipopolysaccharides and other substances produced by pathogenic microorganisms.
pyrogen
 A fever-inducing substance


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? Mentioned in ? References in periodicals archive
 
Fever production in response to exogenous pyrogens is believed to be mediated mostly by cytokine prostaglandin pathways, and neural input is important in the early phases of fever (9).
Dengue and relative bradycardia by Tambyah, Paul Ananth / Emerging Infectious Diseases
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