exocyclic


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

ex·o·cy·clic

(ek'sō-sī'klik, -sik'lik),
Relating to atoms or groups attached to a cyclic structure but not themselves cyclic, for example, the methyl group of toluene. Compare: endocyclic.

exocyclic

/exo·cyc·lic/ (ek″so-sik´lik) denoting one or more atoms attached to a ring but outside it.
References in periodicals archive ?
The most note worthy feature of the hetrocyclic ring is the asymmetry of the exocyclic angles at N(1A) [i30.
Exocyclic malondialdehyde and aromatic DNA adducts in larynx tissues.
N, and =0 groups either in the ring or exocyclic (sticking out).
The Ser158 residue encoded by exon 4 is hydrogen bonded via a side-chain hydroxyl group to the exocyclic hydroxyl 03 of the pyridoxal ring of the pyridoxine 5'-phosphate cofactor; hence, the Ser158Leu mutation is likely to disrupt cofactor binding.
A typical HPLC chromatogram showing co-migration of the exocyclic acrolein--dG adduct peak (UV and radioactivity) from the synthetic standards and from cockerel aorta DNA is shown in Figure 2.
We were expecting the five-membered C-ring formation of steroidal structure of 1 since exocyclic free radical is more stable than endocyclic [11] The Pd-assisted intermolecular cascade cyclization of reduced derivative of acetal 6 also favoured five-membered C-ring in a separate study in our group [12] The dihydroxylation of the steroidal precursor 5 followed by C-ring cleavage with Pb(OAc)4 and condensation of resulting trione would furnish the complete synthesis of steroidal backbone 4 of 1 (scheme-1).
Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts.
Based on these results, metabolite M2 was generated by oxidation of the exocyclic methyl group of emodin, and could be identified as o-hydroxyemodin.