exfoliative dermatitis


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ex·fo·li·a·tive der·ma·ti·tis

rapidly extending erythema followed in a few days by generalized exfoliation with scaling of the skin and associated in some cases with lymphadenopathy or loss of water and electrolytes; may be a drug reaction or associated with various benign dermatoses, lupus erythematosus, or lymphoma, or be of undetermined cause.
Synonym(s): Wilson disease (2)

exfoliative dermatitis

any inflammatory skin disorder characterized by excessive peeling or shedding of skin. The cause is unknown in about half of cases. Known causes include drug reactions, scarlet fever, leukemia, lymphoma, and generalized dermatitis. Treatment is individualized, but care is essential to prevent secondary infection, avoid further irritation, maintain fluid balance, and stabilize body temperature.
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Exfoliative dermatitis

exfoliative dermatitis

Pityriasis rubra Dermatology A condition characterized by scaling and erythema rashes, which may occur in a background of psoriasis or lichen planus

ex·fo·li·a·tive der·ma·ti·tis

(eks-fō'lē-ă-tiv dĕr'mă-tī'tis)
Generalized exfoliation with scaling of the skin and usually with erythema (erythroderma); may be a drug reaction or associated with various benign dermatoses, lupus erythematosus, lymphomas, or of undetermined cause.
Synonym(s): pityriasis rubra, Wilson disease (2) .

Wilson,

Samuel Alexander Kinnier, U.S.-born English neurologist, 1878-1937.
Kinnier Wilson disease - Synonym(s): Wilson disease (1)
Wilson disease - (1) disorder characterized by cirrhosis, degeneration in the basal ganglia of the brain, and deposition of green pigment in the periphery of the cornea. Synonym(s): Kinnier Wilson disease; Strümpell-Westphal disease; Westphal disease; Westphal pseudosclerosis; Westphal-Strümpell pseudosclerosis; Wilson syndrome - (2) generalized exfoliation with scaling of the skin and usually with erythema. Synonym(s): exfoliative dermatitis.
Wilson syndrome - Synonym(s): Wilson disease
exfoliative dermatitis see disease, Wilson's
References in periodicals archive ?
Dapsone-induced photosensitivity can also be a part of dapsone syndrome, (7) where the patient has in addition, fever, exfoliative dermatitis, jaundice, hepatosplenomegaly, generalised lymphadenopathy and pruritus.
One patient on ART developed bullous drug rash, and another patient developed exfoliative dermatitis to rifampicin (mentioned in papulosquamous disorders).
Dapsone hypersensitivity syndrome, granulomatous hepatitis, exfoliative dermatitis, leprosy, dapsone.
The skin biopsy was concluded as being compatible with exfoliative dermatitis.
3 The cardinal features are fever, exfoliative dermatitis, lymphadenopathy, lymphocytosis, methemoglobinemia, hemolytic anemia and hepatotoxicity.
Exfoliative dermatitis is more common with dapsone than other implicated agents.
34% had maculopapular rash, 24% Stevens-Johnson syndrome, 12% exfoliative dermatitis, 10% urticaria, 8% fixed drug eruption, 8% erythema multiforme, 8% bullae, 6% vesicles, 2% lichenoid eruption and 2% scaly eruptions.
Conclusion Frequency distribution of the offending drugs and the adverse reactions revealed that cephradine was responsible for maculopapular rash, sulphonamides for Stevens-Johnson syndrome, indigenous medicines for exfoliative dermatitis, NSAIDs for urticaria and paracetamol for fixed drug eruption.
Out of all patients of exfoliative dermatitis, 4 (66.
The time interval between the introduction of drug and the onset of reaction (mean time) of exfoliative dermatitis was 18 days, maculopapular rash 10 days, fixed drug eruption 10 days, Steven-Johnson syndrome 9 days, erythema multiforme 5 days, urticaria 3 days, lichenoid eruption 2 days and scaly eruption 7 days.