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exfoliatin

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exfoliatin [eks-fo″le-a´tin]
an erythrogenic epidermolytic, heat-stable, acid-labile exotoxin produced by certain strains of Staphylococcus aureus (phage group II), which causes intraepidermal separation by disturbing the adhesive forces between cells in the stratum granulosum to give rise to the clinical manifestations of staphylococcal scalded skin syndrome. Called also epidermolysin.


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Multiplex PCR was used to test for Panton-Valentine leukocidin, toxic shock syndrome toxin 1, and exfoliatin A and B genes (6).
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is responsible for severe infections related to carriage of exotoxins such as the Panton-Valentine leukocidin (PVL), toxic shock syndrome toxin 1 (TSST-1), or exfoliatin A (1).
 
 
 
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