exfoliatin

exfoliatin

 [eks-fo″le-a´tin]
an erythrogenic epidermolytic, heat-stable, acid-labile exotoxin produced by certain strains of Staphylococcus aureus (phage group II), which causes intraepidermal separation by disturbing the adhesive forces between cells in the stratum granulosum to give rise to the clinical manifestations of staphylococcal scalded skin syndrome. Called also epidermolysin.

exfoliatin

(ĕks′fō-lē-ă-tĭn)
A toxin, produced by certain strains of Staphylococcus aureus, responsible for the major dermatological changes in staphylococcal “scalded skin” syndrome in neonates and adults.
References in periodicals archive ?
We used PCR to detect the presence of the PVL- and toxic shock syndrome toxin 1--encoding genes (lukS-lukF PV and tst, respectively), exfoliatin A--and B--encoding genes (eta and etb, respectively) (7), and enterotoxin genes (sea, seb, sec, sed, see, seg, seh, sei, sej, sek, sem, sen, seo, sep, seq, ser) as described by Omoe et al.
Bark of three year old twigs rough, exfoliatin 3 2.
Multiplex PCR was used to test for Panton-Valentine leukocidin, toxic shock syndrome toxin 1, and exfoliatin A and B genes (6).
Genes encoding toxic shock syndrome toxin 1 (n = 4) and exfoliatin A (n = 3) were detected in 7 MSSA isolates.
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is responsible for severe infections related to carriage of exotoxins such as the Panton-Valentine leukocidin (PVL), toxic shock syndrome toxin 1 (TSST-1), or exfoliatin A (1).
Presence of type V cassette, TSST-1, and exfoliatin toxins was assessed by using specific oligonucleotides (sequences are available at www.
A total of 92 isolates (61%) harbored at least 1 toxin gene, most frequently PVL (n = 60), followed by TSST-1 (n = 22) and exfoliatin A (n = 11).