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exencephaly

   Also found in: Wikipedia 0.09 sec.
ex·en·ceph·a·ly (ksn-sf-l)
n.
A condition in which the skull is defective, causing exposure or extrusion of the brain.

exen·ce·phalic (-s-flk) adj.

exencephaly
a congenital defect in which the brain is completely exposed or protrudes through a defect in the cranial vault.

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The supposed actin dependency of anterior but not posterior neuropore closure in mouse embryos (Ybot-Gonzalez and Copp 1999) could thus explain why exencephaly is the dominant NTD observed in VPA-exposed mice (Nau et al.
99-106) reported on the finding that a seven-week-old aborted embryo presented infoldings of the hemispheric neuroepithelium, cranioschisis, exencephaly and excessive vascularity with endothelial proliferation --in short, severe malformation of the brain.
 
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