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exenatide

   Also found in: Wikipedia 0.01 sec.
exenatide,
an antidiabetic drug.
indications This drug is given in combination with metformin or a sulfonylurea to treat type 2 diabetes mellitus.
contraindications Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects of this drug include feeling jittery, restlessness, weakness, nausea, vomiting, diarrhea, dyspepsia, anorexia, gastroesophageal reflux, and weight loss. A life-threatening side effect is hypoglycemia. Common side effects include headache and dizziness.


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One such drug called Exenatide (Byetta), which is a synthetic version of salivary protein found in the gila monster, binds to human GLP - 1 receptors on beta cells in vitro.
13,14) Exenatide (synthetic version of exendin-4, a peptide isolated from the saliva of the Gila monster lizard found in the Arizona desert) is the first GLP-1 mimetic to be approved for adjunctive therapy in patients with type 2 diabetes.
Up to 50 patients across the UAE have tried the new injectable exenatide and several hundred have used the Dipeptidyl Peptidase4 Inhibitor (DPP-4), a new tablet which helps increase the blood glucose and insulin secretion from the body.
 
 
 
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