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etoposide/eto·po·side/ (e″to-po´sīd) a semisynthetic derivative of podophyllotoxin used as the base or the phosphate salt as an antineoplastic, particularly for treating testicular tumors and small cell lung carcinoma.
A semisynthetic derivative of podophyllotoxin that is a mitotic inhibitor used in the treatment of refractory testicular tumors and small cell lung cancer.
an antineoplastic or chemotherapeutic agent and mitotic inhibitor.
indications It is prescribed in the treatment of several forms of cancer, including lymphomas, cancer of the testicles and prostate, and small-cell lung cancer, to prevent tumor cells from dividing and spreading.
contraindications It should not be used if there is an allergy to etoposide or podophyllum. There is a potential adverse effect to the fetus if used by a pregnant patient, and the drug should not be used if breastfeeding.
adverse effects The side effects most often reported include chills, rapid heartbeat, painful or difficult breathing, decreased blood pressure, hair loss, rash, itching, skin discoloration, and digestive disorders.
etoposideOncology A chemotherapeutic active against monocytic leukemia, CNS lymphoma, refractory small cell carcinoma, testicular CA, and KS, which may be co-administered with cyclophosphamide and doxorubicin Adverse effects BM toxicity, hair loss, nausea, incoordination, stomatitis, dyspnea, anorexia. See AIDS, ALL.
etoposideAn anticancer drug derived from a plant poison epipodophyllotoxin. It is used chiefly in the maintenance treatment of acute leukaemia after remission has been achieved and the bone marrow has recovered. It has been given by mouth to treat lung cancer. The drug is on the WHO official list. A brand name is Vepeside.
a derivative of podophyllotoxin with antineoplastic activity; used in the treatment of leukemias.