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etomidate

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etomidate /etom·i·date/ (ĕ-tom´ĭ-dāt) a sedative-hypnotic, administered intravenously for the induction and maintenance of anesthesia.
etomidate
[etom′idāt]
a short-acting, hypnotic nonbarbiturate IV agent for induction of general anesthesia. It has minimal adverse cardiovascular and respiratory effects, thus providing a greater margin of safety in patients with or at risk for heart disease. Adverse effects include transient reduction in adrenal gland cortisol release, pain on injection, and involuntary muscle movements.
etomidate [ĕ-tom´ĭ-dāt]
a sedative and hypnotic, administered intravenously for induction and maintenance of general anesthesia and as a supplement to low-potency anesthetics for maintenance of anesthesia during short operative procedures.
etomidate
an intravenous, nonbarbiturate, fast-inducing anesthetic with no analgesic effect. Also causes suppression of adrenal steroidogenesis and may be used in the treatment of hyperadrenocorticism.
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We have shown that making a version of etomidate that is broken down very quickly in the body reduces the duration of adrenal suppression while retaining etomidate's benefit of keeping blood pressure much more stable than other anaesthetics do," says lead researcher Dr.
Scientists develop potentially safer general anaesthetic by Asian News International
Etomidate has a stable cardiovascular profile, but appears to cause a proportionally greater decrease in CBF than CMR[O.
Traumatic brain injury is a common presentation in theatre by Reed, Anthony; Davies, Gareth / CME: Your SA Journal of CPD
Similar issues of the potential dangers of the prolonged use of medications were seen in the 1980s when etomidate was used for ICU sedation.
Anesthesia: looking back at the last century and forward to the next by Tobias, Joseph D. / Southern Medical Journal
 
 
 
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