ethotoin


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ethotoin

 [eth´o-toin]
an anticonvulsant used in the treatment of grand mal epilepsy and temporal lobe epilepsy, administered orally

ethotoin

/etho·to·in/ (eth´o-toin) an anticonvulsant used in the treatment of grand mal epilepsy and temporal lobe epilepsy.

ethotoin

[eth′ōtō′in]
an anticonvulsant.
indications It is prescribed in the treatment of generalized tonic-clonic and complex-partial seizures.
contraindications Liver disease, hematologic disorders, or known hypersensitivity to this drug or to any hydantoin prohibits its use. It is not recommended for use during pregnancy or lactation.
adverse effects Among the more serious adverse effects are blood disorders, nausea, fatigue, skin rash, alopecia, erythema multiforme, exfoliative dermatitis, and chest pain.

ethotoin

Neurology An anticonvulsant used for generalized tonic clonic seizures Adverse effects BM suppression, aplastic anemia

ethotoin

(eth´ətō´ən),
n brand name: Peganone;
drug class: hydantoin derivative anticonvulsant;
action: inhibits spread of seizure activity in motor cortex;
uses: generalized tonic-clonic or complex-partial seizures.
References in periodicals archive ?
Other drugs assayed at therapeutic concentrations that had no interference included carbamazepine and its epoxide and hydroxy metabolites, oxcarbazepine and it monohydroxylated metabolite, zonisamide, levetiracetam, phenytoin and its metabolites, felbamate, lamotrigine, clonazepam, phenobarbital, primidone, acetaminophen, salicylate, ibuprofen, amitriptyline, nortriptyline, desipramine, doxepin and nordoxepin, imipramine, valproic acid, topiramate, mephenytoin and Nirvanol, amiodarone and desethylamiodarone, methsuximide and normethsuximide, ethotoin, clozapine, and sertraline.
Classification and Pharmacologic Management of Seizures Seizure First Line Agents New/Alternative Agents Simple Partial phenytoin primidone carbamazepine phenobarbital valproic acid gabapentin lamotrigine felbamate topiramate ethotoin mephenytoin Complex partial phenytoin primidone carbamazepine valproic acid phenobarbital mephobarbital gabapentin lamotrigine felbamate topiramate amobarbital Absence clonazepam methsuximide ethosuximide phensuximide valproic acid lamotrigine trimethadione Myoclonic valproic acid clonazepam Tonic Clonic phenytoin/fosphenytoin phenobarbital carbamazepine primidone valproic acid topiramate Stares epilepticus phenytoin/fosphenytoin diazepam lorazepam phenobarbital diazepam secobarbital pentobarbital
5,9] Ethotoin and mephenytoin, second line AEDs in this class, are rapidly absorbed through the gastrointestinal (GI) system.