ethionamide


Also found in: Dictionary, Wikipedia.
Related to ethionamide: isoniazid, Pyrazinamide, cycloserine, ethambutol

ethionamide

 [ĕ-thi″on-am´īd]
an antibacterial effective against Mycobacterium tuberculosis; used in the treatment of pulmonary tuberculosis, administered orally.

ethionamide

/ethi·on·am·ide/ (ĕ-thi″on-am´īd) an antibacterial, effective against Mycobacterium tuberculosis; used in the treatment of pulmonary tuberculosis.

ethionamide

[eth′ē·ənam′īd]
a tuberculostatic antibacterial.
indication It is prescribed for the treatment of tuberculosis in conjunction with other drugs when frontline therapy has failed.
contraindications Existing liver damage or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are skin rash, jaundice, mental depression, and GI side effects.

ethionamide

A drug used in the treatment of LEPROSY or in cases of TUBERCULOSIS resistant to other drugs. The drug is on the WHO official list.

ethionamide

(eth´ēon´əmīd´),
n brand name: Trecator-SC;
drug class: antitubercular;
action: bacteriostatic against Mycobacterium tuberculosis; may inhibit protein synthesis;
uses: pulmonary, extrapulmonary tuberculosis when other antitubercular drugs have failed.
References in periodicals archive ?
inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis.
Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis.
Ortiz de Montellano, The Antituberculosis Drug Ethionamide is Activated by a Flavoprotein Monooxygenase, J.
Treatment for TB includes a combination of anti-tubercular medications including isoniazid, rifampin, pyrazinamide, ethambutol, streptomycin, ethionamide and cycloserine, administered over a span of 12 to 13 months.
So, the second-line ATD (kanamycin, ethionamide, levofloxacin, ethambutol, pyrazinamide, and cycloserine) was started.
either amikacin or kanamycin), any first-line drug to which the isolate is susceptible (Table 1), and the addition of category 3 drugs such as cycloserine/terizidone, ethionamide, and others, such that at least 4 drugs, to which the isolate is likely to be susceptible, are being used
TABLE 1 Drugs that are potential acne triggers Common drugs/drug classes Anabolic steroids (eg, danazol and testosterone) Bromides and iodides Corticosteroids (eg, prednisone) Corticotropin Isoniazid and ethionamide Lithium and barbiturates Phenytoin and trimethadione Less common drugs Azathioprine Cyclosporine Disulfiram Phenobarbital Quinidine Adapted from: Sterry W, et el.
Since 2005, CDC has received reports of difficulty obtaining each of the following SLDs: streptomycin, cycloserine, ethionamide, rifabutin, amikacin, capreomycin, and kanamycin.