ethinyl estradiol


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ethinyl

 [eth´ĭ-nil]
the radical HC≡C—, derived from acetylene.
ethinyl estradiol an estrogen derived from estradiol, used together with a progestational agent as a component of many oral contraceptives, in hormone replacement therapy, and as an antineoplastic in the treatment of advanced breast and prostate cancers; administered orally.

e·thy·nyl es·tra·di·ol

a semisynthetic derivative of 17β-estradiol; active by mouth, with a long half-life, it is among the most potent of known estrogenic compounds; used in oral contraceptive preparations.
Synonym(s): ethinyl estradiol

ethinyl estradiol

(ĕth′ə-nĭl′)
n.
A synthetic estrogen derivative, C20H24O2, used in oral and other contraceptive preparations and in hormone replacement therapy, usually in combination with a progestin.

ethinyl estradiol

[eth′inil]
an estrogen.
indications It is prescribed in the treatment of postmenopausal breast cancer, menstrual cycle irregularities, prostatic cancer, and hypogonadism and for contraception and relief of menopausal vasomotor symptoms.
contraindications Thrombophlebitis, abnormal genital bleeding, known or suspected pregnancy, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are thrombophlebitis, embolism, and hypercalcemia. See also estrogen.

Ethinyl estradiol

A semi-synthetic derivative of estradiol—an estrogen or female sex hormone—used in birth control pills and combined ECPs.

ethinyl estradiol

(eth´inil es´trədī´ol),
n brand names: Estinyl;
drug class: nonsteroidal synthetic estrogen;
action: affects release of pituitary gonadotropins, inhibits ovulation, promotes adequate calcium use in bone structure;
uses: menopause, prostatic cancer, breast cancer, postmenopausal osteoporosis.
References in periodicals archive ?
A one-year, open-label, randomized controlled trial compared the safety of the combined contraceptive vaginal ring with a combined oral contraceptive containing 30 [micro]g ethinyl estradiol and 150 [micro]g levonorgestrel 6 or 3 mg drospirenone (9).
John's wort with oral contraceptives: effects on the pharmacokinetics of norehindrone and ethinyl estradiol, ovarian activity and breakthrough bleeding.
For the urine concentrations of hK5-hK8, hK10, and hK13, we observed a trend toward increased concentrations, but statistical significance was only achieved for hK6, hK10, and hK13 on administration of antiandrogens plus oral ethinyl estradiol.
The data indicate that NuvaRing is comparable to combined oral contraception with 150 [mu]g desogestrel and 30 [mu]g ethinyl estradiol.
More recently, in the December 2004 issue of EHP, Jon Nash and colleagues showed that long-term laboratory exposure to environmental concentrations of the pharmaceutical ethinyl estradiol caused reproductive failure in zebrafish.
One group received additional ethinyl estradiol on days 22-28, which is the typical placebo week of the oral contraceptive pills.
Conclusions: All currently available estrogen-containing oral contraceptives produce a premenstrual fall in ethinyl estradiol concentration equal to or greater than 20 [micro]g.
The Yuzpe 2+2 method involves the administration of a total of 200 [micro]g of ethinyl estradiol and one mg of levonorgestrel (in two equally divided doses), compared to the previous high-dose estrogen methods.
Quartette(TM) features a 91-day regimen, with an 84-day ascending ethinyl estradiol dose designed to minimize unscheduled or breakthrough bleeding, followed by period-stabilizing 10 mcg ethinyl estradiol pills during the traditional seven-day hormone-free interval.
Lupin's Levonorgestrel and Ethinyl Estradiol Tablets are a combined oral contraceptive indicated for the prevention of pregnancy in women who elect to use oral contraceptives as a method of contraception.
03 mg of ethinyl estradiol with 3 mg of drospirenone), approved in 2001, the first COC that contained drospirenone; Yaz (0.
Serum Nestorone[R] and ethinyl estradiol levels, and ovulation inhibition in women using three different dosage combinations of a Nestorone progestogenethinyl estradiol contraceptive vaginal ring on a bleeding-signaled regimen," Contraception 72(1): 49-45.