Also found in: Dictionary, Thesaurus, Wikipedia.
a loop diuretic used orally in the treatment of edema, including that associated with congestive heart failure or hepatic or renal disease, ascites, and hypertension.
eth·a·cryn·ic ac·id(eth'ă-krin'ik as'id),
An unsaturated ketone derivative of aryloxyacetic acid; a potent loop diuretic and a weak antihypertensive;
ethacrynic acid/eth·a·cryn·ic ac·id/ (eth-ah-krin´ik) a loop diuretic used in the treatment of edema, including that associated with congestive heart failure or hepatic or renal disease, ascites, and hypertension.
A compound, C13H12Cl2O4, used as a diuretic primarily to treat severe edema.
a loop diuretic.
indications It is prescribed as a treatment for severe edema, such as nephrotic syndrome, hepatic cirrhoses, and ascites of malignancy. Unlike many other diuretics, ethacrynic acid is not a sulfonamide derivative and can therefore be tolerated by some people who develop hypersensitivity reactions to other diuretics.
contraindications Pregnancy, anuria, or known hypersensitivity to this drug prohibits its use. It is not given to infants.
adverse effects Among the more serious adverse effects are tetany, muscle weakness, cramps, and excessive diuresis. Hearing loss may occur.
ethacrynic acidEtacrynic acid, a LOOP DIURETIC drug. A drug that acts on the tubules in the kidneys to interfere with the reabsorption of water and thus greatly increase the output of urine. A brand name is Edecrin.
eth·a·cryn·ic ac·id(eth'ă-krin'ik as'id)
Unsaturated ketone derivative of aryloxyacetic acid; a potent loop diuretic and a weak antihypertensive;