estrone


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Related to estrone: estriol

estrone

 [es´trōn]
an estrogen isolated from pregnancy urine, the human placenta, and palm kernel oil, and also prepared synthetically; used in estrogen replacement therapy for hypogonadism, ovariectomy, primary ovarian failure, atrophic vaginitis, vasomotor menopausal symptoms such as hot flashes, and vulvar atrophy, and in the treatment of dysfunctional uterine bleeding and advanced prostate cancer. Administered intramuscularly or intravaginally. See also conjugated estrogens and esterified estrogens.

es·trone (E1),

(es'trōn),
A metabolite of 17β-estradiol, commonly found in urine, ovaries, and placenta; has considerably less biologic activity than the parent hormone.

estrone

/es·trone/ (es´trōn) an estrogen isolated from pregnancy urine, human placenta, palm kernel oil, and other sources, also prepared synthetically; for properties and uses, see estrogen.

estrone

(ĕs′trōn′)
n.
An estrogenic hormone, C18H22O2, that is secreted by the ovaries and by fatty tissue. It is the main form of estrogen in postmenopausal women.

estrone

[es′trōn]
a relatively potent endogenous estrogen. Also spelled oestrone.

estrone

E1 An estrogen with very low biologic activity that is the major source of estrogen in children and postmenopausal ♀ ↑ in pregnancy, postmenopausal, ↑ age, obesity, luteal phase of menstrual cycle ↓ in hypogonadism. See Androstendione.

es·trone

(es'trōn)
A metabolite of 17β-estradiol, commonly found in urine, ovaries, and placenta, with considerably less biologic activity than the parent hormone.
Synonym(s): oestrone.

estrone

an oxidation product of estradiol, and androstenedione in the animal body; less active than estradiol and produced in greater quantities in the pregnant female.

estrone sulfate test
1. a pregnancy diagnosis carried out on cow's milk; has very high accuracy but impractical because of lateness of applicability, e.g. maximum at day 105 of pregnancy.
2. a test using serum which detects the presence of a retained testicle in horses with no testicles in the scrotum but which are demonstrating sexual behavior.
References in periodicals archive ?
Taken together, the steroidogenic profile of our co-culture model--given the lack of quantifiable testosterone production but great production of DHEA and, to a lesser extent, androstenedione--indicates that estradiol is produced mainly via the aromatization of androstenedione to estrone and its subsequent rapid conversion to estradiol by 17[beta]-hydroxysteroid dehydrogenase type 1 (HSD17B1).
In vivo, estriol is produced from estrone and directly from androstenedione.
As well, there are higher circulating levels of estradiol and estrone.
Overall, the data suggest that alcohol does not affect estrone levels but may increase estradiol.
Estrone (E1) -- Estrone promotes the formation of bone tissue and is important in preventing osteoporosis.
The literature also indicates the fact that aromatase can turn female androgen, produced by the inner layer adrenal cortex, into a form of estrogen called estrone.
It is believed that high levels of circulating estrogen created by adipose tissue convert androstenedione to estrone, and there is aromatization of androgens.
Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate.
So-called bioidentical hormones are chemically similar to hormones released by the body, including those produced in the ovaries -- estrone, estradiol, estriol, progesterone, testosterone, and dehydroepiandrosterone, to name some.
The list of hormones used in these preparations includes: estradiol, estrone, estriol, progesterone, testosterone, dehydroepiandrosterone (DHEA), and others.
So-called Bioidentical Hormone Replacement Therapy" (BHRT) uses estriol, estradiol, estrone, and progesterone in combinations mixed by compounding pharmacies.