estrogen receptor status


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Related to estrogen receptor status: estrogen receptor positive, Progesterone receptor, progesterone receptor positive

estrogen receptor status

The presence or absence of a receptor to the hormone estrogen on breast cancer cells. Tumors that possess receptors either to estrogen alone or to both estrogen and progesterone are more responsive to estrogen-blocking agents such as tamoxifen than are tumors that lack these receptors.
See also: status
References in periodicals archive ?
These results have illustrated that anethole as a single agent suppresses key pro-inflammatory pathways in human breast cancer cells regardless of estrogen receptor status.
Although clinical factors such as HER2 and estrogen receptor status and therapeutic setting (P = 0.
They found that the maximum life expectancy gain for women who underwent CPM was six months for all scenarios including age, estrogen receptor status, and cancer stage groups.
Estrogen receptor status by immunohistochemistry is superior to the ligand binding assay for predicting response to adjuvant endocrine therapy in breast cancer.
2]) greater than 25 faced a 42%-46% increased risk of developing distant metastasis, even after investigators adjusted for numerous other prognostic factors such as age, tumor size, histologic characteristics, estrogen receptor status, and lymph node involvement.
However, Avemar did inhibit the growth of the ER-negative MDA-MB-231 breast tumors significantly (52%), suggesting to researchers that the mechanism by which the extract works is different from that of the anti- estrogen drugs, and is independent of a breast tumor's estrogen receptor status.

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