estrogen receptor assay

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estrogen receptor assay,

a microscopic examination of breast tumor tissue used to determine the probable response of a tumor to endocrine therapy.

Oncology The ER is a protein found in high concentrations in the cytoplasm of breast, uterus, hypothalamus, and anterior hypophysis cells; ER levels are measured to determine a breast CA's potential for response to hormonal manipulation–60% of breast CAs are 'estrogen positive';¹⁄₂ of ER-positive Pts respond favorably to anti-estrogen–tamoxifen citrate therapy, in contrast to <¹⁄₃ of ER-negative Pts. See 'Flare' phenomenon. Cf Progesterone receptor assay.

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Estrogen-receptor assay			Using the estrogen receptor assay as a pharmacological test system to detect the activity of different fractions, Jarry et al. Analysis of formononetin from black cohosh (Actaea racemosa) by Jiang, B.; Kronenberg, F.; Balick, M.J.; Kennelly, E.J. / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology four years ago and programmed to perform an estrogen receptor assay (see photograph, page 32). Robotics: boon or bust in the lab? by Godolphin, William / Medical Laboratory Observer This combination of in vitro techniques includes the GST-pulldown assay (CARLA test), which detects interactions between ER and a coactivator; a competition binding assay that assesses ligand interactions with the receptor; a yeast-based estrogen receptor assay (YES); and a luciferase reporter assay in cultured MCF-7 cells that reveals transcriptional activation. Estrogenic Activity Assessment of Environmental Chemicals Using in ... by Wahli, Walter / Environmental Health Perspectives			Estrace estradiol estradiol acetate estradiol benzoate estradiol cypionate estradiol hemihydrate estradiol transdermal system estradiol valerate estradiol/estradiol cypionate/estradiol valerate estral estramustine estramustine phosphate sodium estranes estrangement Estrasorb Estratab Estratest Estrela mountain dog estrin estrinization estriol estrogen estrogen dermatitis estrogen fractions test estrogen receptor estrogen receptor assay estrogen receptor negative estrogen receptor positive estrogen replacement therapy estrogen-induced Estrogen-receptor assay estrogen-responsive tissue estrogenic estrogenism estrogens estrone estrophilin estropipate Estrostep estrous estrous cycle estruation estrum estrus estrus cycle ESV ESWL ESWT eszopiclone ET ET CO2			Estrogel estrogen estrogen estrogen Estrogen and Progesterone Receptors Estrogen and Progestin ESTrogen and Stents to Eliminate Restenosis ESTrogen and Stents to Eliminate Restenosis ESTrogen and Stents to Eliminate Restenosis estrogen antagonist Estrogen antagonists Estrogen antagonists Estrogen antagonists estrogen dermatitis estrogen fractions test Estrogen in the Prevention of Atherosclerosis Trial Estrogen patch Estrogen plus Gestagen estrogen poisoning estrogen poisoning estrogen poisoning Estrogen receptor Estrogen receptor Estrogen receptor Estrogen receptor Estrogen receptor Estrogen Receptor 1 Gene Estrogen receptor alpha Estrogen receptor alpha Estrogen Receptor Alpha Knockout estrogen receptor assay Estrogen receptor beta Estrogen receptor beta Estrogen Receptor Binding Cyclophilin Estrogen Receptor DNA-Binding Domain Estrogen Receptor Methylation Estrogen receptor modulators estrogen receptor negative estrogen receptor positive Estrogen Receptor Promoter B Associated Factor 1 Estrogen Receptor Protein Estrogen Receptor Related Protein Estrogen Receptor-Negative Estrogen Receptor-Positive estrogen replacement therapy estrogen replacement therapy estrogen replacement therapy estrogen replacement therapy estrogen replacement therapy Estrogen response element Estrogen therapy Estrogen therapy Estrogen-Androgen Preparation Estrogen-Dependent Pituitary Mass estrogen-induced estrogen-induced transdifferentation estrogen-induced uroliths Estrogen-Progestin Replacement Therapy Estrogen-receptor assay Estrogen-Related Receptor Estrogen-related receptor 1

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