estriol


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Related to estriol: estradiol, estrone

estriol

 [es´tre-ol]
a relatively weak human estrogen that is a metabolic product of estradiol and estrone found in high concentration in the urine of females.

es·tri·ol

(es'trē-ol),
An estrogenic metabolite of estradiol, usually the predominant estrogenic metabolite found in urine (especially during pregnancy); epimers at C-16, C-17, or both, are known as 16-epiestriol, 16,17-epiestriol, and 17-epiestriol.

estriol

/es·tri·ol/ (es´tre-ol) a relatively weak human estrogen (q.v.), being a metabolic product of estradiol and estrone found in high concentrations in urine, especially during pregnancy.

estriol

(ĕs′trī-ôl′, -ōl′, -ŏl′, ĕ-strī′-)
n.
An estrogenic hormone, C18H24O3, that is a metabolite of estradiol and is present chiefly during pregnancy. It is produced by the placenta and is found in the urine of pregnant women.

estriol

[es′trē·ôl]
a relatively weak, naturally occurring human estrogen found in high concentrations in urine. Also spelled oestriol. See also estrogen.

oestriol

The weakest of the three natural human oestrogens; it only appears in significant amounts during pregnancy as it is produced by the placenta from 16-OH DHEA-S, an androgen produced by the foetal liver and adrenal glands.

Pronunciation
Medspeak-UK: pronounced, EE stree oll
Medspeak-US: pronounced, ESS tree oll

estriol

Physiology A steroid hormone, the synthesis of which depends on a sequence of biochemical reactions in the placenta or fetus in a functional compartment, the fetoplacental unit–FPU. See Triple marker.

es·tri·ol

(es'trē-ol)
An estrogenic metabolite of estradiol, usually the predominant estrogenic metabolite found in urine (especially during pregnancy).
Synonym(s): oestriol.

estriol (esˑ·trē·l),

n a form of estrogen synthesized within the liver, used to relieve menopausal complaints. It may increase the risk of endometrial and breast cancers. Also called
E3.

estriol

a relatively weak estrogen, being a metabolic product of estradiol and estrone found in high concentration in the urine of women.
References in periodicals archive ?
Our goal is to make sure salivary estriol testing is available to every woman headed for preterm delivery and to every woman being treated for risk that will never materialize.
80,81) This critical fact helps to explain estriol's anti-estrogen activity, which led a noted researcher in hormone replacement therapy to state: "This unique property of estriol, in contrast to the selective ER [estrogen receptor] alpha binding by other estrogens, imparts to estriol a potential for breast cancer prevention, while other estrogens [estrone and estradiol], would be expected to promote breast cancer.
Preliminary results from the phase 2 clinical trial of sex hormone estriol [1] in women with MS show interesting results that call for further study.
Because MS is an autoimmune disorder in which the body essentially attacks itself, it's believed estriol is released during pregnancy to help suppress the immune system to prevent the body from treating the fetus as an invader.
Basal estrogen production over a 24 hr period (Figure 1D--F) was relatively low in H295R and BeWo cells in monoculture, with estriol production being greater in BeWo cells than in H295R cells (173 [+ or -] 22 vs.
Saliva estriol measurements: an alternative to the assay of serum unconjugated estriol in assessing feto-placental function.
Because UEs is not affected by liver and kidney diseases as well as antibiotics and because conjugated estriol has a short half life, only UEs was selected to be measured in this study.
Each specimen has targeted amounts of AFP, unconjugated estriol, hCG, and inhibin-A, and participants are asked to report the assay results in mass (or international) units; interpretive units (multiples of the median); computed, patient-specific Down-syndrome risk; and the laboratory's suggested follow-up, if any.
8,372,826: Estriol Therapy for Multiple Sclerosis and Other Autoimmune Diseases, which includes claims to Trimesta (oral estriol) in combination with glatiramer acetate injection (Copaxone).
Estriol (E3) is a specific type of estrogen, which is produced by the fetal placental unit.
Women's bodies naturally produce the hormones estrone, estradiol, estriol, and progesterone, and the hormones can also be produced in laboratories.
Multiple Sclerosis (MS) - Two Phase II Clinical Trials Ongoing Completed enrollment of 164 patients in a randomized, double-blind, placebo-controlled, multi-center Phase II clinical trial evaluating the efficacy and safety of our proprietary oral formulation of estriol (Trimesta) for the treatment of relapsing-remitting MS in women.