es·tra·mus·tine phosphate sodium ( s tr -m s t n)n. An antineoplastic agent that combines the actions of estrogen and nitrogen mustard in the treatment of carcinoma of the prostate. |
estramustine phosphate sodium
[es′trəmus′tēn]
an antineoplastic agent.
indications It is prescribed for palliative treatment of metastatic or progressive carcinoma of the prostate.
contraindications Thromboembolytic disorders or known hypersensitivity to this drug prohibits its use.
adverse effects The most serious adverse effects are cerebrovascular insult, myocardial infarction, thrombophlebitis, pulmonary emboli, and congestive heart failure.
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