Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Related to esophagogastroduodenoscopy: endoscopy, hiatal hernia




An endoscope as used in the field of gastroenterology (the medical study of the stomach and intestines) is a thin, flexible tube that uses a lens or miniature camera to view various areas of the gastrointestinal tract. When the procedure is limited to the examination of the inside of the gastrointestinal tract's upper portion, it is called upper endoscopy or esphagogastroduodenoscopy (EGD). With the endoscope, the esophagus (swallowing tube), stomach, and duodenum (first portion of the small intestine) can be easily examined, and abnormalities frequently treated. Patients are usually sedated during the exam.


EGD is performed to evaluate or treat symptoms relating to the upper gastrointestinal tract, such as:
  • upper abdominal or chest pain
  • nausea or vomiting
  • difficulty swallowing (dysphagia)
  • bleeding from the upper intestinal tract
  • anemia (low blood count). EGD can be used to treat certain conditions, such as an area of narrowing or bleeding in the upper gastrointestinal tract
Upper endoscopy is more accurate than x rays for detecting inflammation, ulcers, or tumors. It is used to diagnose early cancer and can frequently determine whether a growth is benign (not cancerous) or malignant (cancerous).
Biopsies (small tissue samples) of inflamed or "suspicious" areas can be obtained and examined by a pathologist. Cell scrapings can also be taken by the introduction of a small brush; this helps in the diagnosis of cancer or infections.
When treating conditions in the upper gastrointestinal tract, small instruments are passed through the endoscope that can stretch narrowed areas (strictures), or remove swallowed objects (such as coins or pins). In addition, bleeding from ulcers or vessels can be treated by a number of endoscopic techniques.
Recent studies have shown the usefulness of endoscopic removal of early tumors of the esophagus or stomach. This is done either with injection of certain materials (like alcohol), or with the use of instruments (like lasers) that burn the tumor. Other techniques combining medications and lasers also show promise.


Patients should inquire as to the doctor's expertise with these procedures, especially when therapy is the main goal. The doctor should be informed of any allergies, medication use, and medical problems.


First, a "topical" (local) medication to numb the gag reflex is given either by spray or is gargled. Patients are usually sedated for the procedure (though not always) by injection of medications into a vein. The endoscopist then has the patient swallow the scope, which is passed through the upper gastrointestinal tract. The lens or camera at the end of the instrument allows the endoscopist to examine each portion of the upper gastrointestinal tract; photos can be taken for reference. Air is pumped in through the instrument to allow proper observation. Biopsies and other procedures can be performed without any significant discomfort.


The upper intestinal tract must be empty for the procedure, so it is necessary NOT to eat or drink for at least 6-12 hours before the exam. Patients need to inquire about taking their medications before the procedure.
Esophagogastroduodenoscopy (EGD) is performed to evaluate or treat symptoms relating to the upper gastrointestinal tract. By inserting an endoscope into the mouth and guiding it through the gastrointestinal tract, the esophagus, stomach, and duodenum can be examined and abnormalities treated.
Esophagogastroduodenoscopy (EGD) is performed to evaluate or treat symptoms relating to the upper gastrointestinal tract. By inserting an endoscope into the mouth and guiding it through the gastrointestinal tract, the esophagus, stomach, and duodenum can be examined and abnormalities treated.
(Illustration by Electronic Illustrators Group.)


Someone should be available to take the person home after the procedure and stay with them for a while; patients will not be able to drive themselves due to sedation. Pain or any other unusual symptoms should be reported immediately.
It is important to recognize early signs of any possible complication. The doctor should be notified if the patient has fever, trouble swallowing, or increasing throat, chest, or abdominal pain.

Key terms

Pathologist — A doctor who specializes in the anatomic (structural) and chemical changes that occur with diseases. These doctors function in the laboratory, examining biopsy specimens, and regulating studies performed by the hospital laboratories (blood tests, urine tests, etc). Pathologists also perform autopsies.


EGD is safe and well tolerated; however, complications can occur as with any procedure. These are most often due to medications used during the procedure, or are related to endoscopic therapy. The overall complication rate of EGD is less than 2%, and many of these complications are minor (such as inflammation of the vein through which medication is given). However, serious ones can and do occur, and almost half of them are related to the heart or lungs. Bleeding or perforations (holes in the gastrointestinal tract) are also reported, especially when tumors or narrowed areas are treated or biopsied. Infections have also been rarely transmitted; improved cleaning techniques should be able to prevent them.



"Understanding Upper Endoscopy." American Society for Gastrointestinal Endoscopy.


EGD; endoscopic examination of the interior of the esophagus, stomach, and initial portion of the duodenum. The procedure usually is done for diagnostic purposes and permits removal of samples of tissue for further study. In some cases the procedure is done to locate and remove a foreign object that has become lodged in the esophagus.
Patient Care. Prior to the procedure, foods and liquids are withheld to facilitate inspection of the mucosa and prevent vomiting and aspiration. A local anesthetic may be used to ease discomfort. Although there should be no severe pain associated with the examination, it can be uncomfortable and sometimes exhausting for the patient. Since there may be some allergic reaction to the anesthetic, the patient is observed for dyspnea, excitement, dizziness, or headache. An emergency tray containing epinephrine and other drugs for treatment of anaphylaxis should be readily available.ƒ

Following any endoscopic examination of the upper gastrointestinal tract the patient is watched for signs of excessive bleeding and perforation. If a local anesthetic has been used, foods and liquids are withheld until normal reflex action returns and there is no danger of aspiration. Hoarseness and a mild sore throat may persist for a few days after the examination.

e·soph·a·go·gas·tro·du·o·de·nos·co·py (EGD),

Endoscopic examination of the esophagus, stomach, and duodenum usually performed using a fiberoptic instrument.


/esoph·a·go·gas·tro·du·od·enos·co·py/ (EGD) (-gas″tro-doo″od-ĕ-nos´kah-pe) endoscopic examination of the esophagus, stomach, and duodenum.

esophagogastroduodenoscopy (EGD)

[ə·sof′əgōgas′ trōdo̅o̅′odənos′kəpe]
an endoscopic test that permits direct visualization of the upper GI tract. Insertion of a long, flexible, fiberoptic-lighted scope allows examination of tumors, varices, mucosal inflammations, hiatal hernias, polyps, ulcers, and obstructions. This test evaluates patients with dysphagia, weight loss, early satiety, upper abdominal pain, ulcer symptoms, or dyspepsia and is also used therapeutically for electrocoagulation, laser coagulation, or injection of sclerosing agents.


Endoscopy An endoscopic examination of the esophagus, stomach, and upper small intestine, usually a tad beyond the ampulla of Vater


(EGD) (ĕ-sof'ă-gō-gas'trō-dū'ŏ-dĕ-nos'kŏ-pē)
Endoscopic examination of the esophagus, stomach, and duodenum, usually performed using a fiberoptic instrument. Motility evaluation, secretion, collection, and tissue sampling may be done. Patient is sedated before the procedure to assess the gag reflex postprocedure. Subsequent assessment of gag reflex is necessary.
Synonym(s): oesophagogastroduodenoscopy.


endoscopic examination of the esophagus, stomach and duodenum.
References in periodicals archive ?
Unsedated small-caliber esophagogastroduodenoscopy (EGD): less expensive and less time-consuming than conventional EGD.
Emergency esophagogastroduodenoscopy (EGD) was performed, and according to EGD findings, there was an active bleeding spot in the distal esophageal diverticulum-Dieulafoy's lesion (Forrest IA).
She received esophagogastroduodenoscopy which revealed GERD Los Angeles Grade B in September 2015.
A total of 120 patients over 16 years of age referred for esophagogastroduodenoscopy (EGD) at the digestive disease outpatient department due to gastrointestinal complains entered this study from May to December of 2015.
Most often the term endoscopy is used to refer to an examination of the upper part of the gastrointestinal tract, known as an esophagogastroduodenoscopy.
Despite these technological advances, there are still certain limitations when using esophagogastroduodenoscopy (EGD) and colonoscopy procedures for detecting and diagnosing small gastrointestinal (GI) tract pathology.
Concordance of Outpatient Esophagogastroduodenoscopy of the Upper Gastrointestinal Tract With Evidence-Based Guidelines.
Prior sedated esophagogastroduodenoscopy and empiric dilation demonstrated no pathology other than gastroesophageal reflux and provided no symptomatic improvement.
6 In this report, we present the unusual case of a patient with catheter occlusion who developed a retroperitoneal hematoma presumably following an elective esophagogastroduodenoscopy (EGD) and colonoscopy.
The study subjects were patients with gastric symptoms and confirmed gastritis, with gastric and duodenal ulcers on esophagogastroduodenoscopy.