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erythropoietic protoporphyria

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erythropoietic protoporphyria
n.
A benign inherited disorder of porphyrin metabolism characterized by enhanced fecal excretion of protoporphyrin and elevated concentration of protoporphyrin in red blood cells, plasma, and feces, with acute solar urticaria or chronic solar eczema appearing quickly upon exposure to sunlight.
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Erythropoietic protoporphyria patients can develop cholestasis, severe hepatic damage, fibrosis, and cirrhosis.
Gene expression profiles associated with inflammation, fibrosis, and ... by Smith, Andrew G. / Environmental Health Perspectives
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