occurs primarily in cells of the spleen and liver, but proximal tubular epithelial cells in the kidney also have this capability.
induced by inflammatory cytokines may also contribute to ACD.
Peris' Prussian blue iron staining was also positive in several macrophages within the lesion, which, along with the presence of acute hemorrhage and erythrophagocytosis
, was indicative of chronic and ongoing hemorrhage.
Numerous parasites (often mimicking histiocytes) are usually present in the necroinflammatory debris and demonstrate erythrophagocytosis
, distinguishing this organism from nonpathogenic E dispar (Figure 4, c and d).
Tumor cells may also decrease erythrocyte survival either via tumor necrosis factor or by causing erythrophagocytosis
Red cell surface changes and erythrophagocytosis
in children with severe Plasmodium falciparum anemia.
was evident in the mesenteric lymph nodes, liver, and spleen.
Red Cells are eliminated through the natural cycle, Erythrophagocytosis
, shown in research studies to completely disintegrate any payload.
Furthermore, presence of xanthochromia, microscopic evidence of erythrophagocytosis
, and hemosiderin-laden macrophages are findings indicating subarachnoid hemorrhage, as long as there has not been a prior traumatic tap.
These cytokines may also contribute to reduced production of Epo and to increased erythrophagocytosis
A further factor could be erythrophagocytosis
, but this is unlikely to contribute significantly to the anaemia, except perhaps in the haemophagocytic syndrome.
Spider bite hemolytic anemia: positive Coombs' test, erythrophagocytosis
, and leukoerythroblastic smear.