erythroleukemia


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erythroleukemia

 [ĕ-rith″ro-loo-ke´me-ah]
a malignant blood dyscrasia, one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.
acute erythroleukemia a form of acute myelogenous leukemia representing erythroleukemia in which malignant leukocyte precursors have proliferated and become predominant.

e·ryth·ro·leu·ke·mi·a

(ĕ-rith'rō-lū-kē'mē-ă),
Simultaneous neoplastic proliferation of erythroblastic and leukoblastic tissues.

erythroleukemia

/eryth·ro·leu·ke·mia/ (ĕ-rith″ro-loo-ke´me-ah) a malignant blood dyscrasia, one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.

erythroleukemia

[-lo̅o̅kē′mē·ə]
Etymology: Gk, erythros + leukos, white, haima, blood
a malignant blood disorder characterized by a proliferation of erythropoietic elements in bone marrow, erythroblasts with bizarre lobulated nuclei, and abnormal myeloblasts in peripheral blood. The disease may have an acute or chronic course. Also called Di Guglielmo's disease, Di Guglielmo's syndrome, erythromyeloblastic leukemia.
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Erythroleukemia

erythroleukemia

Di Guglielmo syndrome Hematology An acute myelocytic leukemia–FAB classification, M6, which is usually acquired affecting the elderly, but rarely also AD Clinical Anemia, fever, hepatosplenomegaly, hemorrhagic diathesis Lab ↑ Erythroblasts in circulation, BM, ↑ gammaglobulins, false positive positive rheumatoid factor, ANA, Coombs antiglobulin Genetics Aneuploidy–63%; cytogenetic defects, especially chromosomes 5 and 7 Prognosis Poor. See French-American-British classification.

e·ryth·ro·leu·ke·mi·a

(ĕ-rith'rō-lū-kē'mē-ă)
Simultaneous neoplastic proliferation of erythroblastic and leukoblastic tissues.
Synonym(s): erythroleukaemia.

erythroleukemia

a malignant blood dyscrasia of dogs and cats; one of the myeloproliferative disorders, with atypical erythroblasts and myeloblasts in the peripheral blood.
References in periodicals archive ?
Expression of ribosomal protein S5 cloned during differentiation and apoptosis in murine erythroleukemia (MEL) cells.
Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells.
2005), such as suppressed cholesterol absorption, increased cholesterol secretion through biliary excretion, induced differentiation of the human erythroleukemia cell line by changing lipooxygenase activity, induced apoptosis, and cell cycle arrest in human osteosarcoma cell line, it has estrogenic effects (Aradhana Rao and Kale, 1992), as well shows antitumor activity (Moalic et al.
The more common variant, referred to as erythremic myelosis, and subsequently as erythroleukemia and erythroid/myeloid leukemia by others, is composed of immature erythroid and myeloid elements.
Differences in human alpha- and beta-globin gene expression in mouse erythroleukemia cells: the role of intragenic sequences.
To see how the NK cells acted directly on cancer cells, the team tested them against K562 erythroleukemia and Raji B-lymphoblastoid cells.
The constructs were expressed in stably transfected mouse erythroleukemia (MEL) cells, and the amount of human [beta]-globin mRNA was measured in total RNA extracted from transfected MEL cells grown for 72 h in the presence of 5 mmol/L hexamethylene bisacetamide, a chemical inducer of erythroid differentiation (20).
High levels of TfR2-mRNA expression in erythroid precursors and erythroleukemia cells point out that TfR2 expression is both cell-cycle and differentiation dependent (15).
Human erythroleukemia K562(S) cells (Lozzio and Lozzio, 1975) were cultured in humidified atmosphere at 5% [CO.
Immunomodulatory and antiproliferative cancer models included ex-vivo human dendritic cell maturation, mice grafted with IFN resistant erythroleukemia and in vitro Daudi cell cultures.
The lack of CD34 expression was somewhat unexpected because this stem cell antigen is expressed on early normal erythroid progenitors (10) and erythroblasts in most erythroleukemia (AML-M6) cases.