erythema nodosum leprosum


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er·y·the·ma no·do·sum le·pro·sum

an acute type of lepromatous reaction with generalized systemic involvement and tender deep cutaneous and subcutaneous nodules of the face, thighs, and arms; usually seen in undiagnosed, untreated, or neglected cases of leprosy. Immune complexes and scanty, fragmented lepra bacilli may be seen in the lesions.

er·y·the·ma no·do·sum le·pro·sum

(er-i-thēmă nō-dōsŭm lep-rōsŭm)
Acute type of lepromatous reaction with generalized systemic involvement and tender deep cutaneous and subcutaneous nodules of the face, thighs, and arms; usually seen in undiagnosed, untreated, or neglected cases of leprosy.

erythema nodosum leprosum

Abbreviation: ENL
A red, nodular vasculitic rash, which may be a complication of the treatment for leprosy. See: lepra

Treatment

Treatment consists of withdrawing therapy against leprosy (clofazimine, steroids, thalidomide).

See also: erythema
References in periodicals archive ?
This applicant is seeking authorization to market a generic version of thalidomide 200 mg tablets in the United States for the acute treatment of cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL).
Food and Drug Administration (FDA) clearance on July 16, 1998 for the acute treatment of cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL) and as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence.
Thalidomide is indicated for the acute treatment of cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL) and as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence.