Erythema nodosum leprosum
in Nepal: a retrospective study of clinical features and response to treatment with prednisolone or thalidomide.
67%), erythema nodosum leprosum
(20%), cutaneous tuberculosis and trichoepithelioma (8% each), Prurigo Nodularis, actinomycosis and epidermoid cyst (6.
Guidelines for the management of severe erythema nodosum leprosum
9% had already had some kind of reactional episode such as erythema nodosum leprosum
(ENH) and/or reversal reactions (RR).
We frequently publish Case Reports describing unusual manifestations or complications of Type 2 leprosy reactions, also known as Erythema Nodosum Leprosum
(ENL), and this issue of Leprosy Review is no exception.
Erythema Nodosum Leprosum
(ENL, Type 2 leprosy reaction) is a severe multi-system disorder characterised by tender crops of cutaneous lesions, neuritis, fever and inflammation of the joints, testes, eyes and bones.
Type 2 lepra reactions, and its cutaneous manifestation, Erythema Nodosum Leprosum
(ENL) are an immune complex mediated systemic condition, often complicating the disease and/or its treatment in cases of the lepromatous spectrum of leprosy.
The slit skin smear was positive and histopathology of the skin from lesions showed ulcerated stratified squamous epithelium, intraepidermal bulla, foamy macrophages with a few giant cells in the dermis, vasculitis with perivascular neutrophilic and lymphocytic infiltration along with dense infiltration of neutrophils in the dermis and subcutaneous fat (septal panniculitis) consistent with features of erythema nodosum leprosum
4) We describe a patient with erythema nodosum leprosum
misdiagnosed as systemic lupus erythematosus, who upon treatment for leprosy developed hemophagocytic lymphohistiocytosis.
He continued to get new lesions of leprosy and recurrent erythema nodosum leprosum
In 2006 he developed erythema nodosum leprosum
and was treated successfully with a short period of prednisone together with thalidomide 100 mg/day that he was still continuing.