SOS repair

(redirected from error-prone repair)

SOS re·pair

a system that repairs severely damaged bases in DNA by base excision and replacement, even if there is no template to guide base selection. This process is a last resort for repair and is often the cause of mutations.
Synonym(s): error-prone repair
An error-prone repair system that functions when E coli’s DNA is damaged by bond-breaking physical agents, thymine starvation, toxins, chemicals—e.g., mitomycin C—and UV light
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The combination of rapid but error-prone repair, the authors suggest, leads basal cells to accumulate a high burden of mutations that ultimately leads to carcinoma.
Error-prone repair of this damage leads to the mutations that initiate breast, prostate, and other types of cancer.
Scientists from NATO member countries introduce new theoretical developments and instrumentation for the non-invasive sensing and imaging of damage in vegetation related to stress from ultraviolet light; identify the cell biological hazards of ultraviolet radiation coupled with other environmental stresses; and examine how ultraviolet light may relate to the production of nitric oxide by plants in terms of DNA damage, error-prone repair cell cycles, and the multiple mechanisms of programmed cell death.

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