ergotamine tartrate


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ergotamine tartrate

[ərgot′əmēn]
a vasoconstrictor that binds to several receptor populations (e.g., alpha-adrenergic, dopamine, serotonin) and, depending upon the receptor, can be an agonist or antagonist.
indications It is prescribed to abort or prevent vascular headaches such as migraines.
contraindications Pregnancy, peripheral vascular disease, infectious disease, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are vomiting, diarrhea, thirst, tingling of fingers and toes, and increased blood pressure. Fetal death may occur if it is used during pregnancy.

ergotamine tartrate

A white crystalline substance that stimulates smooth muscle of blood vessels and the uterus, inducing vasoconstriction and uterine contractions. It is used in the treatment of migraine. Trade names are Ergomar, Ergostat, and Gynergen.
See also: ergotamine

ergotamine tartrate

A drug that causes widened (dilated) arteries to narrow. It is thus useful in the treatment of MIGRAINE. Overdosage is dangerous. The drug is on the WHO official list. Brand names are Lingraine, Medihaler-ergotamine, and, formulated with other drugs, Cafergot and Migril.

ergotamine tartrate

(ur´got´əmēn tar´trāt),
n brand names: Ergomar, Ergostat;
drug class: α-adrenergic blocker;
action: constricts by direct action vascular smooth muscle in peripheral and cranial blood vessels, relaxes uterine muscle;
uses: vascular headache (migraine or histamine), cluster headache.
References in periodicals archive ?
Treves TA, Streiffler M, Korczyn AD: Naproxen sodium versus ergotamine tartrate in the treatment of acute migraine attacks.
But as the disability increases, you're more apt to target right away using a specific agent, whether it's a triptan or a dihydroergotamine or ergotamine tartrate, and in the upper stages you need to consider placing the patient on prophylactic therapy as well," Dr.
Because ergotamine tartrate and dihydroergotamine (DHE) can cause nausea and vomiting, they may be combined with anti-nausea drugs.
For patients who are taking oral ergotamine tartrate, switch the patients to intravenous dihydroergotamine (DHE), and then taper.