ergotamine


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Related to ergotamine: Dihydroergotamine

ergotamine

 [er-got´ah-min]
an alkaloid derived from ergot, used as the tartrate salt in treatment of migraine and cluster headaches; administered orally, sublingually, rectally, or by oral inhalation.

er·got·a·mine

(er-got'ă-mēn),
An alkaloid from ergot, used to relieve migraine; it is a potent stimulant of smooth muscle, particularly of the blood vessels and the uterus, and produces adrenergic blockade (chiefly of the alpha receptors); hydrogenated ergotamine, dihydroergotamine, is less toxic and has fewer side effects. Also available as ergotamine tartrate.

ergotamine

/er·got·amine/ (er-got´ah-min) an alkaloid of ergot; the tartrate salt is used for relief of migraine and cluster headaches.

ergotamine

(ûr-gŏt′ə-mēn′, -mĭn)
n.
A crystalline alkaloid, C33H35N5O5, derived from ergot that induces vasoconstriction and is used especially in treating migraine.

er·got·a·mine

(er-got'ă-mēn)
An alkaloid from ergot, used to relieve migraine; it is a potent stimulant of smooth muscle, particularly of the blood vessels and the uterus, and produces adrenergic blockade (chiefly of the alpha receptors); hydrogenated ergotamine, dihydroergotamine, is less toxic and has fewer side effects. Also available as ergotamine tartrate.

Ergotamine

A drug used to prevent or treat migraine headaches. This can cause vomiting, diarrhea, and convulsions in infants.
Mentioned in: Lactation

ergotamine

; Migril ergot alkaloid used for short-term migraine or cluster headache treatment; it contraindicates concomitant use of some antifungal preparations, certain antiviral reparations, some antimicrobials, serotonin (5-HT1) agonists and cimetidine

er·got·a·mine

(er-got'ă-mēn)
An alkaloid from ergot, used to relieve migraine.

ergotamine

an alkaloid derived from rye ergot; the tartrate is used as an oxytocic.
References in periodicals archive ?
A number of investigators have reported that dihydroergotamine also can be helpful in reducing migraine pain and migraine recurrence rate and that it is a less potent arterial vasoconstrictor than ergotamine and thereby has a lower side effect profile.
Group Animal (n) Dose ([micro]l/kg) Control 10 - Model 10 - Ergotamine 10 1.
Sumatriptan should not be combined with ergotamine or dihydroergotamine.
He was using daily ergotamine and caffeine suppositories, which usually kept the pain at a tolerable level; however, he was regularly visiting the ED.
Her surgeon had noted that her valves appeared glistening white, a telltale sign of injury by a migraine medication known as ergotamine.
The remainder of compounds tested, which included structurally related analogs such as lysergic acid, lysergic acid amide, ergotamine, and methysergide among others, did not exhibit any measurable cross-reactivity (<0.
Although both the US Headache Consortium guidelines and the AAFP/ACP-ASIM guidelines recommend NSAIDs, ergotamine derivatives, and the triptans for treating acute migraines, there is controversy in the literature about how to actually use these drugs.
Two reports have noted gross commissural fusion in patients with ergotamine exposure), (18,19) a finding distinctly unusual for fen-phen valve disease.
The following drugs should not be combined with ritonavir: bepridil (Vascor), amiodarone (Cordarone), flecainide (Tambocor), propafenone (Rythmol), quinidine (Quinidex), simvastatin (Zocor), lovastatin (Mevacor), cisapride (Propulsid), clozapine (Clozaril), midazolam (Versed), triazolam (Halcion), dihydroergotamine (DHE 45) and ergotamine (Cafergot).
Currently, the import of ergotamine, ergometrine, pseudoephedrine, ephedrine, and lysergic acid is conditional with the recommendation from the Narcotics Division.
Other causes include beta-blockers (used to treat high blood pressure), ergotamine preparations (used for migraine headaches), and certain agents used in cancer chemotherapy.
Ergotamine is well known to cause hypertension and should not be given to contract the uterus in a known hypertensive patient.