ergosterol


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ergosterol

 [er-gos´ter-ol]
a sterol occurring in animal and plant tissues which on irradiation by ultraviolet rays converts to vitamin D2, a potent agent for the prevention of rickets, ergocalciferol.

er·gos·ter·ol

(er-gos'tĕr-ol),
The most important of the D2 provitamins; ultraviolet irradiation converts ergosterol to lumisterol, tachysterol, and ergocalciferol; main sterol in yeast, ergot, and molds.
Synonym(s): ergosterin

ergosterol

/er·gos·te·rol/ (er-gos´tĕ-rol) a sterol occurring mainly in yeast and forming ergocalciferol (vitamin D2) on ultraviolet irradiation or electronic bombardment.

ergosterol

(ûr-gŏs′tə-rôl′, -rōl′)
n.
A crystalline sterol, C28H43OH, synthesized by yeast from sugars or derived from ergot and converted to vitamin D2 when exposed to ultraviolet radiation.

ergosterol

[ərgos′tərôl]
an unsaturated hydrocarbon of the vitamin D group isolated from yeast, mushrooms, ergot, and other fungi. When treated with ultraviolet irradiation it is converted into vitamin D2. See also calciferol, viosterol, vitamin D.

er·gos·ter·ol

(ĕr-gos'tĕr-ol)
The most important of the D2 provitamins; ultraviolet irradiation converts ergosterol to lumisterol, tachysterol, and ergocalciferol; main sterol in yeast.

ergosterol

A sterol found in fungal cell membranes which, when exposed to ultraviolet light, is converted into vitamin D2 (ergocalciferol) and to other, toxic, substances.

ergosterol

vitamin D2 provitamin; ergosterol within skin is converted to vitamin D2 by the action of ultraviolet light or sunlight

ergosterol

a sterol occurring in animal and plant tissues which on ultraviolet irradiation becomes a potent antirachitic substance, vitamin D2 (ergocalciferol).
References in periodicals archive ?
Definition of covariates other than ergosterol During the postnatal interviews, several characteristics were recorded every 2 weeks for a period of 2 years: the presence of furry or feathered pets in the house, the presence of smokers inside the house, whether the baby was breast-fed, and the number of hours per week the child was cared for outside the home.
In fungi, the sterol 14[alpha]-demethylase reaction leads to an important precursor of ergosterol.
cicadae was extracted with 95% ethanol, and ergosterol peroxide and 5,6-epoxyergosta-7,22-dien-3-ol were isolated from the C.
27] The mechanism of amphotericin B resistance appears to be an alteration or a decrease in the amount of ergosterol in the cell membrane.
albicans is performed using systemic and topical antifungal, mainly from the group of azole drugs, the main representatives are ketoconazole, miconazole, itraconazole, fluconazole, voriconazole and posaconazole, which have the same mechanism of action, inhibiting the synthesis of ergosterol.
In the absence of oxygen that stimulates ergosterol production by yeast, unsaturated fatty acids and sterols derived from grapes are essential to anaerobic yeast growth (2-4 mg/L phytosterols is required for maximal growth).
The mechanism of action requires its binding to the ergosterol in the fungal membrane, altering the cellular permeability and leading to cell death.
Actua inhibiendo la sintesis de ergosterol, provocando una actividad enzimatica relacionada con la membrana, lo que conduce a un aumento de la permeabilidad e inhibicion del crecimiento celular y su replicacion (Sumano y Ocampo, 1997).
insidiosum para producir esteroides en la membrana plasmatica, como el ergosterol, que es el componente albo de accion de la mayoria de las drogas antimicoticas, que en los hongos alteran la permeabilidad de la membrana celular provocando la lisis celular del hongo (8, 18).
VT-1161, a molecule with high selectivity for fungal CYP51, blocks the production of ergosterol, a key component of the fungal cell membrane, according to the company.
was under the class basidiomycetes and considered as important macrofungi because it was found to have active compound known as ergosterol peroxide [21].
These compounds become effective by inhibiting the biosynthesis of ergosterol which is the main sterol composition in the plasma membrane.