ergosterol


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ergosterol

 [er-gos´ter-ol]
a sterol occurring in animal and plant tissues which on irradiation by ultraviolet rays converts to vitamin D2, a potent agent for the prevention of rickets, ergocalciferol.

er·gos·ter·ol

(er-gos'tĕr-ol),
The most important of the D2 provitamins; ultraviolet irradiation converts ergosterol to lumisterol, tachysterol, and ergocalciferol; main sterol in yeast, ergot, and molds.
Synonym(s): ergosterin

ergosterol

/er·gos·te·rol/ (er-gos´tĕ-rol) a sterol occurring mainly in yeast and forming ergocalciferol (vitamin D2) on ultraviolet irradiation or electronic bombardment.

ergosterol

(ûr-gŏs′tə-rôl′, -rōl′)
n.
A crystalline sterol, C28H43OH, synthesized by yeast from sugars or derived from ergot and converted to vitamin D2 when exposed to ultraviolet radiation.

ergosterol

[ərgos′tərôl]
an unsaturated hydrocarbon of the vitamin D group isolated from yeast, mushrooms, ergot, and other fungi. When treated with ultraviolet irradiation it is converted into vitamin D2. See also calciferol, viosterol, vitamin D.

er·gos·ter·ol

(ĕr-gos'tĕr-ol)
The most important of the D2 provitamins; ultraviolet irradiation converts ergosterol to lumisterol, tachysterol, and ergocalciferol; main sterol in yeast.

ergosterol

A sterol found in fungal cell membranes which, when exposed to ultraviolet light, is converted into vitamin D2 (ergocalciferol) and to other, toxic, substances.

ergosterol

vitamin D2 provitamin; ergosterol within skin is converted to vitamin D2 by the action of ultraviolet light or sunlight

ergosterol

a sterol occurring in animal and plant tissues which on ultraviolet irradiation becomes a potent antirachitic substance, vitamin D2 (ergocalciferol).
References in periodicals archive ?
Ocimum sanctum essential oil and its active principles exert their antifungal activity by disrupting ergosterol biosynthesis and membrane integrity.
The extraction of ergosterol was as described by Chong et al.
So "it is possible that ergosterol inhibitors could be useful as a partner drug in future combination therapies," the researchers said.
From a holistic viewpoint, use of the whole mushroom with its B-glucans, PSK, PSP, and ergosterol provides even a stronger antitumor activity.
Ergosterol peroxide isolated from Ganoderma lucidum abolishes microRNA miR-378-mediated tumor cells on chemoresistance.
Polyenes bind directly to the unique fungal sterol ergosterol and compromise membrane function.
It was combined in turn with four poorly water soluble drugs of different properties and biomedical functions: carvedilol (a nonselective adrenergic receptor blocker, indicated in the treatment of mild-to-moderate congestive heart failure), itraconazole (an antifungal agent that impairs ergosterol synthesis, used among others against histoplasmosis, cryptococcal meningitis, and aspergillosis), nevirapine (a potent, non-nucleoside reverse transcriptase inhibitor used for treatment of HIV infection and AIDS), and nimodipine (a calcium channel blockader with preferential cerebrovascular activity).
Ergosterol makes vitamin D from exposure to sunlight much like we do.
1-995- Use of solid-phase extraction to determine ergosterol concentrations in plant tissue colonized by fungi.
1-4,14) The antifungal agents target the Prototheca sp cell wall, which is composed of 4% ergosterol.
Plant sterols such as [beta]-sitosterol and campesterol in serum originate from oral consumption, whereas a few endogenous sterols such as lathosterol, desmosterol, and ergosterol are precursors in the biosynthesis of cholesterol and vitamin D (24, 25).