ergonovine maleate

er·go·no·vine ma·le·ate

a powerful oxytocic agent; this action is more prominent, and other actions of ergot (for example, vasoconstriction, central nervous system stimulation, adrenergic blockade) are less prominent than for other ergot alkaloids; effective orally and parenterally.
Synonym(s): ergometrine maleate

ergonovine maleate

[ur′gōnō′vēn]
an oxytocic ergot alkaloid. Also called ergometrine maleate.
indications It is prescribed to contract the uterus in the treatment or prevention of postpartum or postabortion hemorrhage caused by uterine atony.
contraindications Pregnancy, peripheral vascular disease, elevated blood pressure, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are hypertension, nausea, headache, blurred vision, and hypersensitivity reactions. Fetal death may result from use of the drug in pregnancy.

er·go·no·vine ma·le·ate

Powerful oxytocic agent; this action is more prominent, and other actions of ergot (e.g., vasoconstriction, central nervous system stimulation, adrenergic blockade) are less prominent than for other ergot alkaloids; effective orally and parenterally.
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Administration of ergonovine maleate precipitated chest discomfort accompanied by diffuse right coronary spasm exceeding 40% diameter reduction.
99%), ergonovine maleate (Sigma, E-6500, lot 54H1077), propranolol hydrochloride (Sigma, P-8688, lot 88H4092) and oxytocin (N.
Methylergonovine and ergonovine maleate are inexpensive and highly efficacious.