erb-B2

erb-B2

(erb'be'too')
A member of the erb-B family of oncogenes. This oncogene is overexpressed in some cancers and is associated with progression of breast cancer. Its protein product contains part of the epidermal growth factor (EGF) receptor. Synonym: HER2 See: oncogene; epidermal growth factor; breast cancer
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Professor Arteaga's research focuses on the role of growth factor receptors, such as the EGF receptor, erb-B2 and TGF-beta receptors in the progression of breast cancer, as well as the development of anti- cancer molecular therapeutics.