equipoise


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Related to equipoise: Clinical equipoise

e·qui·poise

(e'kwi-poyz),
1. Equilibrium; an even distribution of weight.
2. In epidemiology, a state of uncertainty as to the balance of benefits and harm that may result from two or more therapeutic regimens. A state of e. is an indication for a randomized controlled trial.
[equi- + M.E. poisen, weigh, fr. Fr. peser, fr. L.L. peso, fr. L. penso]

equipoise

EBM
A state of genuine uncertainty regarding the benefits or disadvantages of either therapeutic arm of a clinical trial; because a clinical investigator may become biased as a clinical study progresses, given his or her perception of the benefits or adverse effects of one of the therapeutic regimens being evaluated, he or she may enroll fewer and fewer patients in the arm perceived to be less beneficial (due to ethical considerations), and may ultimately defeat the very purpose of the study due to lack of patients in the control arm. A moral exit to this dilemma known as “clinical equipoise” is possible, since genuine uncertainty exists in the expert medical community at large; the investigator may thus continue to enroll control patients “blindly”, despite his or her bias.
  
Health fraud
(upper case) A device invented at the turn of the 20th century by Heracles Sanche, the self-proclaimed Discoverer of the Laws of Spontaneous Cure of Disease, which he alleged supplied the needed electrical force to the system and optimised the absorption of oxygen from the lungs through heat; the device’s opened metal cylinder proved to be empty.

equipoise

Medical ethics A state of uncertainty regarding the pros or cons of either therapeutic arm in a clinical trial

equipoise

(ē′kwĭ-poyz″, ĕk′wĭ-)
In the design of clinical trials, a state in which the risks and benefits of alternative treatments offered during the trial are balanced, so that no pre-existing advantage is known to exist for one treatment arm over the other. This is a required ethical consideration in clinical research.
References in periodicals archive ?
He described a benign equipoise amongst strong organizations, an equipoise constrained by a wider public consensus that empowered the central government and its social welfare agenda.
The general government uses the Welfare Clause and the Commerce Clause as if they're elastic clauses that can be stretched to any purpose they see fit; however, the Constitution is a document of perfect equipoise, or equal distribution, meaning that one clause cannot be read as if to stand alone.
candidate at Area Study Centre for Africa, North & South America, Quaid-i-Azam University Islamabad defended her doctoral dissertation bearing title A Quest for Equipoise vis-a-vis Culture Crisis: Bapsi Sidhwa and Contemporary Emergent Literature in the United States here the other day.
candidate at Area Study Centre for Africa, North & South America, Quaid-i-Azam University Islamabad defended her doctoral dissertation bearing title "A Quest for Equipoise vis-a-vis Culture Crisis: Bapsi Sidhwa and Contemporary Emergent Literature in the United States" here the other day.
privacy considerations, and equipoise in public health research does not obviously support Dawson's claim to coherence.
in Palatine, Ill Most presentations at the company annual meeting are one-dimensional and are more likely to depress individuals with their use of silly props like beach balls than to help them reach equipoise.
The highlight of Santa Anita's opening meeting, the 'Big 'Cap' was worth $108,400 to the winner and attracted most of the best horses in training, including Mate (sixth), topweight Equipoise (seventh), Twenty Grand (tenth), Faireno and Head Play.
Collaboration with climate and customs and clients and coworkers seems the key to this delicate yet robust equipoise.
In recent years, the Report has hosted a lively scholarly conversation about moral justification and informed decision-making in clinical research, including exposition of the moral norms of research, reexaminations of voluntariness and paternalism in research decision-making, and comparisons of equipoise and nonexploitation.
Clute defines equipoise as describing "a very loose category of stories which [.
In other words, clinical equipoise requires that at the start of a RCT [t]here exist .
I am feeling absolutely proud and I would like to copy Rahman in equipoise.