equianalgesic dose


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e·qui·an·al·ge·sic dose

the qualitative ratio between actual milligram potency of comparable analgesics required to achieve the equivalent therapeutic effect.

equianalgesic dose

[ē′kwē·an′əljē′sik]
a dose of one analgesic that is equivalent in pain-relieving effects to that of another analgesic. This equivalence permits substitution of medications to prevent possible adverse effects of one of the drugs. The term is also applied to equivalent alternative dose sizes and routes of administration.

equianalgesic dose

A dose of one form of analgesic drug equivalent in pain-relieving effect to another analgesic. In pain control, this equivalence permits substitution of one analgesic to avoid undesired side effects from another.
See also: dose

e·qui·an·al·ge·sic dose

(ēkwē-anăl-jēzik dōs)
Qualitative ratio between actual milligram potency of comparable analgesics required to achieve the equivalent therapeutic effect.
References in periodicals archive ?
In rodents, studies examining combinations of oxycodone and morphine (111) and methadone and morphine (112) have supported the hypothesis that mixtures of opioids are synergistic, leading to better pain relief and fewer opioid-related side-effects compared with equianalgesic doses of each opioid given alone (113).
Patients considered opioid tolerant are those who are taking at least 60 mg oral morphine/day, 25 mcg transdermal fentanyl/hour, 30 mg oral oxycodone/day, 8 mg oral hydromorphone/day, 25 mg oral oxymorphone/day, or an equianalgesic dose of another opioid for one week or longer.
Patients considered to be opioid tolerant are those who are taking at least 60 mg oral morphine per day, or at least 30 mg of oral oxycodone per day, or at least 12 mg hydromorphone per day, or an equianalgesic dose of another opioid, for a week or longer.
Patients considered opioid tolerant are those who are taking at least 60 mg of oral morphine/daily, or at least 25 mcg transdermal fentanyl/hour, or at least 30 mg of oral oxycodone daily, or at least 8 mg oral hydromorphone daily, at least 25 mg oral oxymorphone daily or an equianalgesic dose of another opioid for a week or longer.
Patients considered opioid tolerant are those who are taking at least 60 mg morphine/day, at least 25 mcg transdermal fentanyl/hour, at least 30 mg of oxycodone daily, at least 8 mg oral hydromorphone daily or an equianalgesic dose of another opioid for a week or longer.