epoprostenol


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Related to epoprostenol: alprostadil, Bosentan, Epoprostenol sodium

epoprostenol

 [e″po-pros´tĕ-nol]
name for prostacyclin when used pharmaceutically; it is used in the form of the sodium salt as an inhibitor of platelet aggregation for blood contacting nonbiological systems, as in renal dialysis, as a pulmonary antihypertensive, and as a vasodilator.

pros·ta·cy·clin

(pros'tă-sī'klin),
A potent natural inhibitor of platelet aggregation and a powerful vasodilator.

epoprostenol

/ep·o·pro·sten·ol/ (e″po-pros´tĕ-nol) name for prostacyclin when used pharmaceutically; used in the form of the sodium salt as an inhibitor of platelet aggregation when blood contacts nonbiological systems, a pulmonary antihypertensive, and a vasodilator.

epoprostenol

[e′popros′tĕnol]
name for prostacyclin when used pharmaceutically. It is used in the form of the sodium salt as an inhibitor of platelet aggregation for blood contacting nonbiological systems, as in renal dialysis; as a pulmonary antihypertensive; and as a vasodilator.

Beraprost

An oral prostacyclin PGI2 analogue with vasodilator, antiplatelet, and cytoprotective effects, used to manage pulmonary arterial hypertension. Beraprost improves exercise capacity and symptoms in NYHA-functional class-II and -III patients with PAH and, in particular, in those with primary pulmonary hypertension.

Adverse effects
Headache, facial flushing, vasodilation.

epoprostenol

Prostacyclin. A powerful inhibitor of clumping of blood platelets and thus of blood clotting. It is used with heart-lung (cardiopulmonary bypass) machines and artificial kidneys (dialysis machines) to preserve the platelets in the blood being pumped through them. Epoprostenol also widens (dilates) arteries. A brand name is Flotan.

epoprostenol

References in periodicals archive ?
Epoprostenol had swift antiplatelet activity and vasodilatory properties, and longterm treatment was associated with significant reductions in pulmonary vascular resistance, going beyond immediate vasodilation.
No se encontraron diferencias significativas entre urapidil e hidralazina, entre epoprostenol e hidralazina, entre labetalol y bloqueadores de canales de calcio y entre labetalol y metildopa.
Treatment options for pulmonary hypertension associated with scleroderma include the endothelin receptor antagonist bosentan (Tracleer); the phosphodiesterase inhibitors sildenafil (Revatio), vardenafil (Levitra) or tadalafil (Adcicra); and various prostacyclin analogs, such as epoprostenol (Flolan), treprostinil (Remodulin) and iloprost (Ventavis).
Ayrica terbutalin, epoprostenol, salbutamol, kivrim diuretikleri, kalsiyum antagonistleri ve Ginko biloba ekstraktlarinin da kismi yarar sagladigi bildirilmistir.
Influence of 3, 4', 5-trihydroxystibene-3-mono-D-glucoside on vascular endothelial epoprostenol and platelet aggregation.
Effect of chitosan on lingual hemostasis in rabbits with platelet dysfunction induced by epoprostenol.
M2 PHARMA-August 27, 2010-Actelion says FDA OKs brand name VELETRI for epoprostenol for injection therapy(C)2010 M2 COMMUNICATIONS
In addition, the company said that today Epoprostenol for Injection, an improved formulation of epoprostenol that is stable at room temperature, has become available for the treatment of primary pulmonary hypertension and pulmonary hypertension associated with scleroderma spectrum of disease in NYHA Class III and Class IV patients who do not respond adequately to conventional therapy.
Reasonable alternatives to inhaled nitric oxide for acute vasoreactivity testing are intravenous epoprostenol (Flolan) and intravenous adenosine.