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epithelioid sarcoma

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epithelioid sarcoma
A low-grade sarcoma of the upper extremity, ♂:♀ ratio, 2:1, of Pts age 10-35 Treatment Wide local excision or amputation DiffDx-Benign Fibromatosis, fibrous histiocytoma, nodular fasciitis, infectious granuloma, necrobiosis lipoidica, rheumatoid nodule DiffDx-malignant Synovial sarcoma, fibrosarcoma, melanoma Prognosis Recurrence is common; 45% metastasize–eg, to lung, regional lymph nodes, scalp


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Epithelioid sarcoma has only been rarely reported to involve the pleura.
One patient who had received six infusions of infliximab 5 mg/kg had an epithelioid sarcoma that was reported approximately 9 mo after the last study infusion.
The histologic differential diagnosis is predicated on whether the tumor is biphasic or monophasic; it includes adenocarcinoma, spindle cell carcinoma, fibrosarcoma, malignant peripheral nerve sheath tumor, glomangiopericytoma (hemangiopericytoma), leiomyosarcoma, malignant melanoma, epithelioid sarcoma, and angiosarcoma.
 
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