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epistasis
(redirected from epistatic)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.03 sec.
e·pis·ta·sis (-pst-ss)
n. pl. e·pis·ta·ses (-sz)
1. A film that forms over the surface of a urine specimen.
2. An interaction between nonallelic genes, especially an interaction in which one gene suppresses the expression of another.
3. The suppression of a bodily discharge or secretion.

epi·static (p-sttk) adj.

epistasis
[epis′təsis]
Etymology: Gk, a standing
1 suppression of a secretion or excretion, as of blood, menses, or lochia.
2 an interaction between genes at different loci in which one gene masks or suppresses the expression of the other. Epistasis, which is nonallelic and therefore different from dominance, may be caused by the presence of homozygous recessive alleles at one gene pair, as occurs in the Bombay phenotype, or by the presence of a dominant allele at one locus that counteracts the expression of a dominant allele at the other locus. Compare dominance. epistatic, adj.

epistasis [ĕ-pis´tah-sis]
1. suppression of a secretion or excretion, as of blood, menses, or lochia.
2. the interaction between genes at different loci, as a result of which one hereditary character is unexpressed, or is masked by the superimposition of another upon it. See also dominance. adj., adj epistat´ic.

epistasis,
n gene interaction where a gene at a particular locus supercedes or obscures the expression of another gene at a different locus.

epistasis
non-allelic masking of one gene by another, e.g. the masking of the black gene by the orange gene in tortoiseshell cats.


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Epistatic Epistatic genetic variance is also produced by interactions among alleles but at different loci rather than at the same locus.
20) However, the APOE [epsilon]4 allele is neither necessary nor sufficient to cause the disease, indicating epistatic or epigenetic mechanisms.
Identifying specific genes is further complicated by incomplete penetrance, pleiotropy (multiple effects of a single gene), and epistatic interactions (several genes interacting in the same individuals) [115].
 
 
 
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